Variability in Trypanosoma cruzi susceptibility among species of kissing bugs (Hemiptera: Reduviidae: Triatominae) in Mexico.

IF 1.5 4区医学 Q3 PARASITOLOGY

Folia Parasitologica Pub Date : 2025-04-01 DOI:10.14411/fp.2025.011

Alberto Antonio-Campos, Ernesto Ramirez-Moreno, Victor Sanchez-Cordero, Nancy Rivas, Ricardo Alejandre-Aguilar

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引用次数: 0

Abstract

Chagas disease, caused by the kinetoplastid Trypanosoma cruzi (Chagas, 1909), and transmitted by triatomine bugs, poses a significant public health challenge. Variability in the susceptibility of different triatomine species to T. cruzi infection can profoundly influence disease transmission dynamics and control measures. In this study, we assessed the susceptibility to T. cruzi infection in the first and third nymphal stages across eight triatomine species to T. cruzi infection using experimental inoculation with the NINOA strain and optical microscopy. The evaluated species were Dipetalogaster maximus (Uhler), Triatoma bassolsae (Alejandre-Aguilar, Nogueda-Torres, Cortéz-Jiménez, Jurberg, Galvão, Carcaballo), T. infestans (Klug), T. lecticularia (Stål), T. mexicana (Herrich-Schaeffer), T. pallidipennis (Stål), T. phyllosoma (Burmeister) and T. picturata (Usinger). The results indicated that T. bassolsae exhibited the highest susceptibility to infection, followed by T. pallidipennis and D. maximus. Our analysis also revealed that T. cruzi (NINOA) infection was significantly associated with triatomine species rather than nymphal stage (p < 0.0001), with substantial variability observed in susceptibility among species (p < 0.001). We ranked triatomine species susceptibility to T. cruzi infection as follows: T. bassolsae > D. maximus = T. pallidipennis = T. picturata = T. mexicana > T. phyllosoma = T. lecticularia = T. infestans. These findings enhance our understanding of T. cruzi transmission dynamics and offer valuable insights for the development of effective control strategies against this neglected tropical disease.

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来源期刊

Folia Parasitologica 医学-寄生虫学

CiteScore

2.70

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： FOLIA PARASITOLOGICA, issued in online versions, is an international journal that covers the whole field of general, systematic, ecological and experimental parasitology. It publishes original research papers, research notes and review articles. Contributions from all branches of animal parasitology, such as morphology, taxonomy, biology, biochemistry, physiology, immunology, molecular biology and evolution of parasites, and host-parasite relationships, are eligible. Novelty and importance in the international (not local or regional) context are required. New geographical records of parasites, records of new hosts, regional parasite and/or host surveys (if they constitute the principal substance of manuscript), local/regional prevalence surveys of diseases, local/regional studies on epidemiology of well known diseases and of parasite impact on human/animal health, case reports, routine clinical studies and testing of established diagnostic or treatment procedures, will not be considered. One species description will also not be considered unless they include more general information, such as new diagnostic characters, host-parasite associations, phylogenetic implications, etc. Manuscripts found suitable on submission will be reviewed by at least two reviewers.