{"title":"[Progress in the therapy of corneal neovascularization].","authors":"C X Yan, M X Liu, L Jin, L J Zhang","doi":"10.3760/cma.j.cn112142-20240829-00374","DOIUrl":null,"url":null,"abstract":"<p><p>Corneal neovascularization, a severe pathologic change of the ocular surface, is usually caused by complex pathogeneses, and leads to severe vision damage and eventually corneal blindness. The applications of anti-inflammatory and anti-angiogenic drugs as well as keratoplasty have proved to have certain therapeutic effects. However, there are still numerous barriers that have not yet been fully overcome, prompting a trend towards treatment with multidisciplinary techniques. In this review, we summarize the latest research progress and give an overview of the techniques and strategies for treatment of corneal neovascularization in recent years based on the new mechanistic findings, aiming to improve the therapeutic efficiency and precision.</p>","PeriodicalId":39688,"journal":{"name":"中华眼科杂志","volume":"61 4","pages":"310-315"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华眼科杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/cma.j.cn112142-20240829-00374","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Corneal neovascularization, a severe pathologic change of the ocular surface, is usually caused by complex pathogeneses, and leads to severe vision damage and eventually corneal blindness. The applications of anti-inflammatory and anti-angiogenic drugs as well as keratoplasty have proved to have certain therapeutic effects. However, there are still numerous barriers that have not yet been fully overcome, prompting a trend towards treatment with multidisciplinary techniques. In this review, we summarize the latest research progress and give an overview of the techniques and strategies for treatment of corneal neovascularization in recent years based on the new mechanistic findings, aiming to improve the therapeutic efficiency and precision.