A Meta-Synthesis Exploring Daily Experiences of Adults With Coeliac Disease in Adhering to a Gluten-Free Diet

IF 2.9 3区医学 Q3 NUTRITION & DIETETICS

Journal of Human Nutrition and Dietetics Pub Date : 2025-04-08 DOI:10.1111/jhn.70043

Anna Kowalczuk, Fiona Moor

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引用次数: 0

Abstract

Background

Coeliac disease (CD) is an autoimmune disease affecting 1.4% of the population worldwide. The only treatment for this condition is a strict, lifelong gluten-free diet (GFD). Although the complexity of this condition is recognised, the definitive follow-up strategy and long-term management have still not been developed in the United Kingdom (UK) and Australia. This meta-synthesis aimed to explore the experiences of patients living with CD who follow the GFD in the UK and Australia.

Methods

A systematic search for primary qualitative literature related to experiences of patients with CD on a GFD and a meta-synthesis of the results were conducted. Healthcare-relevant online databases were screened: Academic Search Complete, CINAHL, MEDLINE, and Scopus, followed by reference list searching. A defined inclusion criteria were used to identify relevant studies. The data synthesis from the literature followed the thematic synthesis approach. A clear description of the methodology and peer review were applied to ensure transparency.

Results

A total of 286 studies were screened for eligibility. Of those, six studies met the inclusion criteria. The experiences of 198 patients living with CD were analysed and reported. Five analytical themes emerged through the thematic synthesis process: acceptance and adaptation, dietary burden, cost burden, socialising, and importance of support. All themes were found to impact patients' quality of life (QoL). The overall quality of the reviewed studies was described as good.

Conclusion

This meta-synthesis revealed insights into the daily experiences of patients with CD in adhering to a GFD in the UK and Australia, being the first secondary qualitative study to explore this phenomenon. It highlighted the need for the development of defined strategies for patient follow-up to provide holistic care, considering the complexities of this condition and its impact on both physical and psychological domains.

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一项探讨成人乳糜泻坚持无麸质饮食的日常经历的综合研究

乳糜泻（CD）是一种影响全球1.4%人口的自身免疫性疾病。这种情况的唯一治疗方法是严格的终身无麸质饮食（GFD）。虽然认识到这种情况的复杂性，但在英国和澳大利亚仍未制定明确的后续策略和长期管理。本综合研究旨在探讨英国和澳大利亚遵循GFD的乳糜泻患者的经历。方法系统检索与CD患者在GFD上的经历相关的主要定性文献，并对结果进行meta综合。筛选与医疗保健相关的在线数据库：Academic Search Complete、CINAHL、MEDLINE和Scopus，然后进行参考文献列表搜索。采用明确的纳入标准来确定相关研究。文献数据综合采用主题综合方法。为确保透明度，采用了对方法和同行审查的明确说明。结果共筛选286项研究。其中，6项研究符合纳入标准。对198例乳糜泻患者的生活经历进行了分析和报道。通过主题综合过程，出现了五个分析主题：接受和适应、饮食负担、成本负担、社会化和支持的重要性。所有主题均影响患者的生活质量（QoL）。所审查研究的总体质量被描述为良好。结论：这项荟萃综合研究揭示了英国和澳大利亚坚持GFD治疗的CD患者的日常经历，是探索这一现象的第一个二级定性研究。它强调需要制定明确的患者随访策略，以提供整体护理，考虑到这种情况的复杂性及其对身体和心理领域的影响。

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来源期刊

Journal of Human Nutrition and Dietetics 医学-营养学

CiteScore

5.30

自引率

15.20%

发文量

133

审稿时长

6-12 weeks

期刊介绍： Journal of Human Nutrition and Dietetics is an international peer-reviewed journal publishing papers in applied nutrition and dietetics. Papers are therefore welcomed on: - Clinical nutrition and the practice of therapeutic dietetics - Clinical and professional guidelines - Public health nutrition and nutritional epidemiology - Dietary surveys and dietary assessment methodology - Health promotion and intervention studies and their effectiveness - Obesity, weight control and body composition - Research on psychological determinants of healthy and unhealthy eating behaviour. Focus can for example be on attitudes, brain correlates of food reward processing, social influences, impulsivity, cognitive control, cognitive processes, dieting, psychological treatments. - Appetite, Food intake and nutritional status - Nutrigenomics and molecular nutrition - The journal does not publish animal research The journal is published in an online-only format. No printed issue of this title will be produced but authors will still be able to order offprints of their own articles.