Chondromyxoid fibroma in the oro-facial region: A case report

Abstract

Chondromyxoid Fibroma (CMF) is an uncommon, slow-growing benign chondroblast tumour with hypocellular or chondromyxoid tissue and multinucleated cells. Similar pathologies to aggressive tumours, such as chondrosarcoma, make CMFs harder to identify. This lesion may cause painful swelling or enlargement for weeks or years or may be identified accidentally during radiological scanning. A 24-year-old girl was diagnosed with CMF affecting the right upper jaw. She came with a developing mass, periodic swelling discomfort, facial asymmetry, and the H/O of surgery at the same region 5 years earlier. The patient had a right-sided Class Ⅲ Maxillectomy performed under General Anaesthesia. There were no immediate post-operative problems however, delayed issues occurred. Chondromyxoid fibroma is uncommon and has various sites, making diagnosis difficult and often exclusionary. However, it has a good prognosis with a recurrence rate of up to 80 % in curettage-only patients and a 2 % chance of malignant transformation. This example emphasizes the importance of a thorough clinical examination and histological comparison of CMFs with comparable lesions for optimal therapy. As shown in our case timely intervention can improve results and quality of life for affected cases.