Impact of dietary exogenous feed enzymes on performance, nutrient digestibility, and ruminal fermentation parameters in beef cattle: a meta-analysis

IF 4 2区农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Animal Pub Date : 2025-03-14 DOI:10.1016/j.animal.2025.101481

I.M. Ferreira , H.C. Mantovani , M. Vedovatto , A.S. Cardoso , A.A. Rodrigues , B.G.C. Homem , M.J.I. de Abreu , A.N. Rodrigues , L.H. Cursino Batista , J.S. de Oliveira , F.L. Viquez-Umana , A.H.P.M Assumpção , G.R. Siqueira , F.D. de Resende

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引用次数: 0

Abstract

Exogenous feed enzymes (EFE) are incorporated into beef cattle diets to improve nutrient utilization and animal performance. This meta-analysis estimates the effects of EFE inclusion on beef cattle performance, feed intake, nutrient digestibility, and ruminal fermentation parameters, while also identifying factors influencing these outcomes. We initially screened 94 articles, and 23 studies met the eligibility criteria, contributing data from up to 83 treatment means. The magnitude of the effect (size effect) was determined using weighted mean differences (WMD) between the EFE-treated and control groups (diets without EFE inclusion). Heterogeneity was assessed through meta-regression and subgroup analysis. Results indicated that EFE inclusion did not affect final BW (P ≥ 0.871), DM intake (P ≥ 0.467), average daily gain (P ≥ 0.145), or feed efficiency (P ≥ 0.417). However, a significant increase in hot carcass weight (P = 0.047; WMD = 2.21 kg) was observed. The inclusion of EFE in the diet did not affect the profile of ruminal short-chain fat acid (P ≥ 0.225) or ruminal ammonia nitrogen concentration (N-NH₃; P = 0.143). However, EFE inclusion improved the digestibility of DM (P < 0.01; WMD = 16.9 g/kg), CP (P = 0.003; WMD = 20.2 g/kg), and NDF (P = 0.003; WMD = 20.2), with no effect on organic matter or starch digestibility (P ≥ 0.388). Heterogeneity was low (I² < 25%) for most performance and nutrient digestibility outcomes, indicating consistent effect size estimates. Moderate heterogeneity (P ≤ 0.057; I² = 25–50%) was noted for DM and NDF digestibility, with EFE application explaining 28.2% of the variability in DM digestibility (P = 0.032), and fully accounting for the heterogeneity in NDF digestibility (P = 0.045). High heterogeneity was found in ruminal fermentation parameters (P < 0.01; I² > 50%). Funnel plot analysis revealed no publication bias for most variables (P ≥ 0.10). Overall, this meta-analysis demonstrates that EFE inclusion in beef cattle diets increases hot carcass weight, likely due to enhanced digestibility of DM, CP, and NDF, without affecting rumen fermentation parameters.

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外源性饲料酶（EFE）被添加到肉牛日粮中，以提高养分利用率和动物性能。本荟萃分析估计了添加 EFE 对肉牛性能、采食量、营养物质消化率和瘤胃发酵参数的影响，同时还确定了影响这些结果的因素。我们初步筛选了 94 篇文章，有 23 项研究符合资格标准，提供了多达 83 个处理平均值的数据。采用 EFE 处理组与对照组（未添加 EFE 的日粮）之间的加权平均差 (WMD) 来确定效应的大小（规模效应）。通过元回归和亚组分析评估了异质性。结果表明，添加 EFE 不会影响最终体重（P ≥ 0.871）、DM 摄入量（P ≥ 0.467）、平均日增重（P ≥ 0.145）或饲料效率（P ≥ 0.417）。不过，热胴体重有明显增加（P = 0.047；WMD = 2.21 kg）。日粮中添加 EFE 不会影响瘤胃短链脂肪酸（P ≥ 0.225）或瘤胃氨氮浓度（N-NH3；P = 0.143）。然而，添加 EFE 提高了 DM（P < 0.01；WMD = 16.9 克/千克）、CP（P = 0.003；WMD = 20.2 克/千克）和 NDF（P = 0.003；WMD = 20.2）的消化率，但对有机物或淀粉消化率没有影响（P ≥ 0.388）。大多数性能和营养消化率结果的异质性较低（I2 < 25%），表明效应大小估计值一致。在 DM 和 NDF 消化率方面存在中度异质性（P ≤ 0.057；I2 = 25-50%），EFE 的应用解释了 DM 消化率 28.2% 的变异性（P = 0.032），并完全解释了 NDF 消化率的异质性（P = 0.045）。瘤胃发酵参数的异质性很高（P < 0.01; I2 >50%）。漏斗图分析表明，大多数变量没有发表偏倚（P ≥ 0.10）。总之，这项荟萃分析表明，在肉牛日粮中添加 EFE 可增加热胴体重量，这可能是由于提高了 DM、CP 和 NDF 的消化率，而不会影响瘤胃发酵参数。

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来源期刊

Animal 农林科学-奶制品与动物科学

CiteScore

7.50

自引率

2.80%

发文量

246

审稿时长

3 months

期刊介绍： Editorial board animal attracts the best research in animal biology and animal systems from across the spectrum of the agricultural, biomedical, and environmental sciences. It is the central element in an exciting collaboration between the British Society of Animal Science (BSAS), Institut National de la Recherche Agronomique (INRA) and the European Federation of Animal Science (EAAP) and represents a merging of three scientific journals: Animal Science; Animal Research; Reproduction, Nutrition, Development. animal publishes original cutting-edge research, ''hot'' topics and horizon-scanning reviews on animal-related aspects of the life sciences at the molecular, cellular, organ, whole animal and production system levels. The main subject areas include: breeding and genetics; nutrition; physiology and functional biology of systems; behaviour, health and welfare; farming systems, environmental impact and climate change; product quality, human health and well-being. Animal models and papers dealing with the integration of research between these topics and their impact on the environment and people are particularly welcome.