Outcomes Associated with Non-standard Configuration of Renal Branches in Aortic Endografts.

IF 1.4 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE
Anastasia Dean, Summer Hassan, William Yoon, Kevin Mani, Anders Wanhainen, David Lindström
{"title":"Outcomes Associated with Non-standard Configuration of Renal Branches in Aortic Endografts.","authors":"Anastasia Dean, Summer Hassan, William Yoon, Kevin Mani, Anders Wanhainen, David Lindström","doi":"10.1016/j.avsg.2025.03.014","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Endovascular repair of thoracoabdominal and pararenal aortic aneurysms (TAAAs and PAAAs) involves the use of branched stent grafts to perfuse visceral arteries. Non-standard renal branch configuration, such as \"ballerina,\" may be required as a bailout technique in challenging anatomical or technical situations. This configuration may result in altered hemodynamic stress, increasing the risk of branch-related complications.</p><p><strong>Methods: </strong>This single-center, retrospective cohort study analyzed outcomes of renal branches in standard and non-standard configurations (outside IFU) following endovascular repair of TAAAs and PAAAs. Renal branches were categorized as standard or ballerina (branch connected to the contralateral renal artery, ≥90° radial deviation from the cuff to the arterial orifice) based on postoperative imaging. Adverse outcomes, including branch occlusion, thrombus formation, and the need for re-intervention, were recorded. Kaplan-Meier analysis was used to assess complication-free survival.</p><p><strong>Results: </strong>A total of 97 renal branches in 56 patients were analyzed and followed for a median of 25 months. Non-standard configuration (11 branches) had significantly higher adverse event rates (45%) compared to standard configurations (16%, p = 0.04). Complications among the eleven ballerina branches included two occlusions, one thrombus, and two compressions requiring re-lining. In standard configurations, branch occlusions were the most common complication (14%). Kaplan-Meier analysis demonstrated significantly reduced complication-free survival in non-standard configurations compared to standard configurations (median 54 vs 594 days, p = 0.02).</p><p><strong>Conclusion: </strong>Bailout non-standard renal branch configurations are associated with a high rate of serious adverse events. Intensified postoperative imaging surveillance with readiness for re-intervention and optimized antithrombotic therapy should be considered in these cases.</p>","PeriodicalId":8061,"journal":{"name":"Annals of vascular surgery","volume":" ","pages":""},"PeriodicalIF":1.4000,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of vascular surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.avsg.2025.03.014","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Endovascular repair of thoracoabdominal and pararenal aortic aneurysms (TAAAs and PAAAs) involves the use of branched stent grafts to perfuse visceral arteries. Non-standard renal branch configuration, such as "ballerina," may be required as a bailout technique in challenging anatomical or technical situations. This configuration may result in altered hemodynamic stress, increasing the risk of branch-related complications.

Methods: This single-center, retrospective cohort study analyzed outcomes of renal branches in standard and non-standard configurations (outside IFU) following endovascular repair of TAAAs and PAAAs. Renal branches were categorized as standard or ballerina (branch connected to the contralateral renal artery, ≥90° radial deviation from the cuff to the arterial orifice) based on postoperative imaging. Adverse outcomes, including branch occlusion, thrombus formation, and the need for re-intervention, were recorded. Kaplan-Meier analysis was used to assess complication-free survival.

Results: A total of 97 renal branches in 56 patients were analyzed and followed for a median of 25 months. Non-standard configuration (11 branches) had significantly higher adverse event rates (45%) compared to standard configurations (16%, p = 0.04). Complications among the eleven ballerina branches included two occlusions, one thrombus, and two compressions requiring re-lining. In standard configurations, branch occlusions were the most common complication (14%). Kaplan-Meier analysis demonstrated significantly reduced complication-free survival in non-standard configurations compared to standard configurations (median 54 vs 594 days, p = 0.02).

Conclusion: Bailout non-standard renal branch configurations are associated with a high rate of serious adverse events. Intensified postoperative imaging surveillance with readiness for re-intervention and optimized antithrombotic therapy should be considered in these cases.

主动脉内移植物肾分支非标准配置的相关结果
背景:胸腹主动脉瘤和主动脉旁动脉瘤的血管内修复涉及使用分支支架移植物灌注内脏动脉。在具有挑战性的解剖或技术情况下,可能需要使用 "芭蕾舞 "等非标准肾分支配置作为救助技术。这种配置可能会导致血流动力学压力改变,增加发生肾分支相关并发症的风险:这项单中心回顾性队列研究分析了TAAA和PAAA血管内修复术后标准和非标准配置(IFU外)肾分支的预后。根据术后成像结果,肾分支被分为标准和芭蕾舞分支(与对侧肾动脉相连的分支,从袖带到动脉口的径向偏差≥90°)。记录了不良后果,包括分支闭塞、血栓形成和需要再次介入。采用 Kaplan-Meier 分析法评估无并发症生存率:结果:共对 56 名患者的 97 个肾分支进行了分析,随访时间中位数为 25 个月。与标准配置(16%,P = 0.04)相比,非标准配置(11 个分支)的不良事件发生率(45%)明显更高。11 个芭蕾舞分支的并发症包括两个闭塞、一个血栓和两个需要重新衬垫的压迫。在标准配置中,分支闭塞是最常见的并发症(14%)。Kaplan-Meier 分析显示,与标准配置相比,非标准配置的无并发症生存期明显缩短(中位 54 天 vs 594 天,P = 0.02):结论:保外非标准肾分支配置与高严重不良事件发生率相关。结论:保外非标准肾支配置与高严重不良事件发生率有关,应考虑在这些病例中加强术后影像学监测,为再次介入和优化抗血栓治疗做好准备。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
3.00
自引率
13.30%
发文量
603
审稿时长
50 days
期刊介绍: Annals of Vascular Surgery, published eight times a year, invites original manuscripts reporting clinical and experimental work in vascular surgery for peer review. Articles may be submitted for the following sections of the journal: Clinical Research (reports of clinical series, new drug or medical device trials) Basic Science Research (new investigations, experimental work) Case Reports (reports on a limited series of patients) General Reviews (scholarly review of the existing literature on a relevant topic) Developments in Endovascular and Endoscopic Surgery Selected Techniques (technical maneuvers) Historical Notes (interesting vignettes from the early days of vascular surgery) Editorials/Correspondence
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信