Few-shot biomedical NER empowered by LLMs-assisted data augmentation and multi-scale feature extraction.

IF 4 3区 生物学 Q1 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Di Zhao, Wenxuan Mu, Xiangxing Jia, Shuang Liu, Yonghe Chu, Jiana Meng, Hongfei Lin
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引用次数: 0

Abstract

Named Entity Recognition (NER) is a fundamental task in processing biomedical text. Due to the limited availability of labeled data, researchers have investigated few-shot learning methods to tackle this challenge. However, replicating the performance of fully supervised methods remains difficult in few-shot scenarios. This paper addresses two main issues. In terms of data augmentation, existing methods primarily focus on replacing content in the original text, which can potentially distort the semantics. Furthermore, current approaches often neglect sentence features at multiple scales. To overcome these challenges, we utilize ChatGPT to generate enriched data with distinct semantics for the same entities, thereby reducing noisy data. Simultaneously, we employ dynamic convolution to capture multi-scale semantic information in sentences and enhance feature representation based on PubMedBERT. We evaluated the experiments on four biomedical NER datasets (BC5CDR-Disease, NCBI, BioNLP11EPI, BioNLP13GE), and the results exceeded the current state-of-the-art models in most few-shot scenarios, including mainstream large language models like ChatGPT. The results confirm the effectiveness of the proposed method in data augmentation and model generalization.

命名实体识别(NER)是处理生物医学文本的一项基本任务。由于标注数据的可用性有限,研究人员研究了少量学习方法来应对这一挑战。然而,在少数几次学习的情况下,复制完全监督方法的性能仍然很困难。本文主要解决两个问题。在数据增强方面,现有方法主要侧重于替换原文内容,这可能会扭曲语义。此外,现有方法往往忽视了多种尺度的句子特征。为了克服这些挑战,我们利用 ChatGPT 为相同的实体生成具有不同语义的丰富数据,从而减少噪声数据。同时,我们利用动态卷积捕捉句子中的多尺度语义信息,并基于 PubMedBERT 增强特征表示。我们在四个生物医学 NER 数据集(BC5CDR-Disease、NCBI、BioNLP11EPI、BioNLP13GE)上进行了实验评估,结果显示,在大多数少数几个场景中,实验结果都超过了目前最先进的模型,包括主流的大型语言模型,如 ChatGPT。这些结果证实了所提出的方法在数据扩增和模型泛化方面的有效性。
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来源期刊
Biodata Mining
Biodata Mining MATHEMATICAL & COMPUTATIONAL BIOLOGY-
CiteScore
7.90
自引率
0.00%
发文量
28
审稿时长
23 weeks
期刊介绍: BioData Mining is an open access, open peer-reviewed journal encompassing research on all aspects of data mining applied to high-dimensional biological and biomedical data, focusing on computational aspects of knowledge discovery from large-scale genetic, transcriptomic, genomic, proteomic, and metabolomic data. Topical areas include, but are not limited to: -Development, evaluation, and application of novel data mining and machine learning algorithms. -Adaptation, evaluation, and application of traditional data mining and machine learning algorithms. -Open-source software for the application of data mining and machine learning algorithms. -Design, development and integration of databases, software and web services for the storage, management, retrieval, and analysis of data from large scale studies. -Pre-processing, post-processing, modeling, and interpretation of data mining and machine learning results for biological interpretation and knowledge discovery.
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