Wentao Li, Xianjin Hu, Fanghui Li, Yao Tong, Aobo Gong, Ying Cao, Zexi Li, Wenzhai Cao, Dayong Zhang, Min Xu, Xuechuan Dan, Kui Li, Rongzheng Yue, Kaijun Cui, Hongde Hu, Hua Fu, Rui Zeng
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引用次数: 0
Abstract
Most studies have followed patients with persistent atrial fibrillation (PeAF) using 12-lead or 24-h Holter electrocardiography, but this may overestimate the effectiveness of pulsed field ablation (PFA) in the treatment of PeAF. This study aimed to investigate the feasibility of PFA in patients with PeAF and follow-up using insertable cardiac monitoring that can provide information on the actual status of atrial arrhythmia (AA) recurrence after PFA. We prospectively enrolled 49 patients with PeAF who underwent PFA strategy comprising superior vena cava isolation, pulmonary vein isolation, and posterior wall box isolation between December 2022 and January 2024. After median follow-up of 14.1 months, 30 patients (61.22%) had zero AA burden. Kaplan-Meier analysis show that the freedom from recurrence increased with arrhythmia duration thresholds, from 59.54% to 80.50% (duration < 2 min vs. duration > 48 h, p = 0.040). Safety events occurred in two patients (one transient ischemic attack and one pseudoaneurysm). PFA is an effective modality for the treatment of patients with PeAF.
大多数研究使用12导联或24小时动态心电图对持续性心房颤动(PeAF)患者进行随访,但这可能高估了脉冲场消融(PFA)治疗PeAF的有效性。本研究旨在探讨PFA在PeAF患者中的可行性,并使用可插入心脏监护仪进行随访,该监护仪可以提供PFA后心房心律失常(AA)复发的实际情况。我们前瞻性地招募了49例PeAF患者,他们在2022年12月至2024年1月期间接受了PFA策略,包括上腔静脉隔离、肺静脉隔离和后壁盒隔离。中位随访14.1个月后,30例患者(61.22%)AA负担为零。Kaplan-Meier分析显示,随着心律失常持续时间阈值的增加,复发率增加,从59.54%增加到80.50%(持续时间< 2 min vs.持续时间bb0 48 h, p = 0.040)。2例患者发生安全事件(1例短暂性脑缺血发作和1例假性动脉瘤)。PFA是治疗PeAF患者的一种有效方式。
期刊介绍:
Pacing and Clinical Electrophysiology (PACE) is the foremost peer-reviewed journal in the field of pacing and implantable cardioversion defibrillation, publishing over 50% of all English language articles in its field, featuring original, review, and didactic papers, and case reports related to daily practice. Articles also include editorials, book reviews, Musings on humane topics relevant to medical practice, electrophysiology (EP) rounds, device rounds, and information concerning the quality of devices used in the practice of the specialty.