Non-alcoholic fatty liver disease and drug induced liver injury: A metabolic storm waiting to happen.

IF 2.5 Q2 GASTROENTEROLOGY & HEPATOLOGY
Vanessa Pamela Salolin Vargas, Marisa Gasbarra, Ernesto Calderon-Martinez, Yash R Shah, Dushyant Singh Dahiya, Mauricio Garcia Saenz de Sicilia
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引用次数: 0

Abstract

In this editorial, we comment on the article by Zhao et al which highlighted how patients having nonalcoholic fatty liver disease (NAFLD) were more susceptible to drug-induced lung injury (DILI). This article looked at the downstream effects of metabolic profiles and biochemical processes after medication and substance use. Although previous studies looked at how NAFLD and DILI were related, there is a lack of information on the consequences of everyday medication and substance use. NAFLD is one of the most common chronic liver diseases worldwide and it has been found to be closely related to metabolic syndrome and cardiovascular disease. The aim of this editorial is to analyze the interaction between NAFLD and DILI, what clinical manifestations can occur and what the prognosis of these patients will be.

非酒精性脂肪性肝病和药物性肝损伤:一场即将发生的代谢风暴
在这篇社论中,我们评论了Zhao等人的文章,该文章强调了非酒精性脂肪性肝病(NAFLD)患者更容易发生药物性肺损伤(DILI)。本文研究了药物和物质使用后代谢谱和生化过程的下游影响。虽然以前的研究着眼于NAFLD和DILI之间的关系,但缺乏关于日常药物和药物使用后果的信息。NAFLD是世界范围内最常见的慢性肝病之一,与代谢综合征和心血管疾病密切相关。这篇社论的目的是分析NAFLD和DILI之间的相互作用,可能发生的临床表现以及这些患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
World Journal of Hepatology
World Journal of Hepatology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
4.10
自引率
4.20%
发文量
172
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