Bladder Cancer in Lebanon: An Updated Epidemiological Comparison with Global Regions and a Comprehensive Review of Risk Factors.

IF 2.5 4区 医学 Q3 ONCOLOGY
Cancer Control Pub Date : 2025-01-01 Epub Date: 2025-04-01 DOI:10.1177/10732748251330696
Najla A Lakkis, Mona H Osman, Reem M Abdallah, Nour M Mokalled
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引用次数: 0

Abstract

ObjectivesThis study aims to analyze urinary bladder cancer (UBC) incidence rates in Lebanon over a 12-year period (2005-2016) and compare them with rates in other countries. It also discusses UBC risk factors in Lebanon.IntroductionLebanon has one of the highest estimated age-standardized incidence rates (ASIRw) of UBC worldwide.MethodsData on UBC were obtained from the Lebanese national cancer registry for the years 2005-2016. The study calculated age-standardized incidence rates (ASIRw) and age-specific rates per 100 000 population. It also estimated the population attributable fractions of smoking, water pollution, and air pollution for UBC incidence in Lebanon in 2016. However, limited data precluded sensitivity analyses, potentially affecting the robustness of the estimates.ResultsDuring this period, UBC ranked as the third most common cancer in males (12.9% of all new cancer cases) and the eighth most common in females (2.8% of all new cancer cases), excluding non-melanoma skin cancer. The average ASIRw was 28.8 in men and 6.6 in women, placing Lebanon among the countries with the highest UBC incidence rates globally. UBC incidence rates increased with age. Estimates indicated that 46.4% of UBC cases in the Lebanese population were attributed to current smoking, 8.6% to water pollution with disinfection byproducts, and 6.0% to air pollution with PM2.5.ConclusionThis study underscores the urgent need to mitigate UBC risk in Lebanon through tobacco control and by reducing exposure to preventable environmental and occupational risk factors, including tobacco smoking, water pollution, and air pollution.

本研究旨在分析黎巴嫩 12 年间(2005-2016 年)的尿路膀胱癌(UBC)发病率,并将其与其他国家的发病率进行比较。导言黎巴嫩是全球尿路膀胱癌估计年龄标准化发病率(ASIRw)最高的国家之一。方法2005-2016年的尿路膀胱癌数据来自黎巴嫩国家癌症登记处。研究计算了每 10 万人的年龄标准化发病率(ASIRw)和特定年龄发病率。研究还估算了2016年黎巴嫩UBC发病率中吸烟、水污染和空气污染的人群可归因分数。然而,由于数据有限,无法进行敏感性分析,这可能会影响估算结果的稳健性。结果在此期间,除非黑色素瘤皮肤癌外,尿路结石是男性第三大最常见癌症(占所有新发癌症病例的 12.9%),是女性第八大最常见癌症(占所有新发癌症病例的 2.8%)。男性的平均 ASIRw 为 28.8,女性为 6.6,黎巴嫩是全球 UBC 发病率最高的国家之一。UBC 发病率随着年龄的增长而增加。据估计,黎巴嫩人口中46.4%的UBC病例归因于当前吸烟,8.6%归因于消毒副产物造成的水污染,6.0%归因于PM2.5造成的空气污染。结论这项研究强调,黎巴嫩迫切需要通过烟草控制和减少暴露于可预防的环境和职业风险因素(包括吸烟、水污染和空气污染)来降低UBC风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Cancer Control
Cancer Control ONCOLOGY-
CiteScore
3.80
自引率
0.00%
发文量
148
审稿时长
>12 weeks
期刊介绍: Cancer Control is a JCR-ranked, peer-reviewed open access journal whose mission is to advance the prevention, detection, diagnosis, treatment, and palliative care of cancer by enabling researchers, doctors, policymakers, and other healthcare professionals to freely share research along the cancer control continuum. Our vision is a world where gold-standard cancer care is the norm, not the exception.
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