Primary chest wall sarcoma: advances in surgical management and outcomes.

IF 1.4 Q3 ORTHOPEDICS

European Journal of Orthopaedic Surgery and Traumatology Pub Date : 2025-04-01 DOI:10.1007/s00590-025-04260-1

Shin Tanaka, Eiji Nakata, Tsuyoshi Ryuko, Takuto Itano, Yasuaki Tomioka, Kazuhiko Shien, Ken Suzawa, Kentaroh Miyoshi, Mikio Okazaki, Seiichiro Sugimoto, Toshifumi Ozaki, Shinichi Toyooka

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引用次数: 0

Abstract

Purpose: Although rare, primary chest wall sarcomas are complex malignancies necessitating optimal local control and comprehensive treatment. This study aimed to review 9 years of cases of primary chest wall sarcomas at a single institution, focusing on their histology, surgical management, and prognosis.

Methods: A retrospective analysis was performed on 19 patients undergoing chest wall resection for sarcoma from 2012 to 2020. Data on demographics, tumor specifics, resection extent, and adjuvant therapies were collected. Surgical and postoperative outcomes were also assessed.

Results: The median patient age was 64 years. Chondrosarcoma was the most common histology. R0 resection was achieved in all patients, with early postoperative complications occurring in 11% of the patients. Robust chest wall reconstruction was performed, resulting in minimal respiratory complications. The 5-year overall survival and disease-free survival rates were 94% and 68%, respectively. Tumor size and patient age were significant prognostic factors for local recurrence.

Conclusion: Comprehensive surgical resection, coupled with multidisciplinary preoperative planning, achieves favorable outcomes. Patients aged ≥ 70 years and with tumor size ≥ 5 cm (P = .047) should be carefully followed up for local recurrence.

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原发性胸壁肉瘤：外科治疗和预后的进展。

目的：原发性胸壁肉瘤虽然罕见，但却是一种复杂的恶性肿瘤，需要适当的局部控制和综合治疗。本研究旨在回顾同一医院9年来的原发性胸壁肉瘤病例，重点关注其组织学、手术治疗和预后。方法：回顾性分析2012年至2020年接受胸壁肉瘤切除术的19例患者。收集了人口统计学、肿瘤特征、切除范围和辅助治疗的数据。手术和术后结果也进行了评估。结果：患者中位年龄为64岁。软骨肉瘤是最常见的组织学。所有患者均实现了R0切除，11%的患者出现了早期术后并发症。进行了坚固的胸壁重建，导致最小的呼吸并发症。5年总生存率为94%，无病生存率为68%。肿瘤大小和患者年龄是局部复发的重要预后因素。结论：综合手术切除配合多学科术前规划，取得良好效果。年龄≥70岁，肿瘤大小≥5 cm （P = 0.047）的患者应仔细随访，以防局部复发。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Orthopaedic Surgery and Traumatology 医学-整形外科

CiteScore

3.00

自引率

5.90%

发文量

265

审稿时长

3-8 weeks

期刊介绍： The European Journal of Orthopaedic Surgery and Traumatology (EJOST) aims to publish high quality Orthopedic scientific work. The objective of our journal is to disseminate meaningful, impactful, clinically relevant work from each and every region of the world, that has the potential to change and or inform clinical practice.