Inflammatory myofibroblastic tumor of the bladder treated with partial cystectomy: Case report.

Abstract

Introduction: Inflammatory myofibroblastic tumor (IMT) is a rare form of tumor which is composed of fibroblastic and myofibroblastic spindle cells, with an inflammatory infiltrate of lymphocytes, plasma cells, and eosinophils. IMT may arise from different organs, but it is infrequent in the urinary bladder and usually manifests as haematuria.

Case presentation: Here we report a 20 years old male patient with no previous history of trauma or surgery presented with gross hematuria and severe anaemia. Further workup with transurethral resection biopsy and immunohistochemistry are supportive of IMT and we did partial cystectomy. Follow up cystoscopy after 3 months showed normal bladder wall.

Clinical discussion: An inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal tumor. It comprises differentiated myofibroblastic spindle cells with numerous plasma cells and/or lymphocyte infiltrate. According to the World Health Organisation (WHO) classification, IMT is a low grade or borderline mesenchymal tumor. The commonest site for IMT is the lung, but it rarely occur in the genitourinary tract. Hematuria is the commonest manifestation of bladder IMT. Transurethral resection of bladder tumor (TURBT) and partial cystectomy are treatment modalities.

Conclusion: IMT of the bladder is a rare tumor which manifests mainly with hematuria. Although TURBT is the standard treatment for IMT, partial cystectomy has lower recurrence rate.