Association of Smoking and Alcohol with Abdominal Aortic Calcification in the General Middle-Aged and Elderly Populations.

IF 1.9 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Reviews in cardiovascular medicine Pub Date : 2025-03-21 eCollection Date: 2025-03-01 DOI:10.31083/RCM26087
Yinze Ji, Naqiang Lv, Aimin Dang
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引用次数: 0

Abstract

Background: Research results on the association between alcohol consumption and abdominal aortic calcification (AAC) has yielded inconsistent results. There is a paucity of evidence on the association of smoking and alcohol consumption with AAC in the general middle-aged and elderly population, including age subgroups. This study utilizes nationwide survey data to explore these associations.

Methods: Data from middle-aged and elderly National Health and Nutrition Examination Survey (NHANES) 2013-2014 participants receiving dual X-ray absorptiometry were analyzed. AAC severity was assessed using a scoring system with a maximum value of 24. Presence of AAC was defined as an AAC score >0, and severe AAC as an AAC score ≥6. Binary logistic regression was employed for analyzing the association of smoking and alcohol consumption-related indices with the presence of AAC, while cumulative odds logistic regression explored their associations with severe AAC.

Results: Data of 3135 participants were analyzed. Investigation in the entire population found that smoking history was linked to both AAC and severe AAC. In contrast, alcohol consumption history was not linked to AAC or severe AAC. After adjusting for confounders, the findings confirmed a significant association of smoking history with AAC and severe AAC. No significant associations were found for current alcohol consumption with either AAC or severe AAC. Compared with never smokers, former smokers and current smokers experienced increased AAC risk. Former smokers had a significantly lower AAC risk compared to current smokers. Compared with never alcohol consumers, neither former nor current alcohol consumers experienced a different AAC risk. No difference in AAC risk was found between former and current alcohol consumers. Individuals consuming more than 2 drinks of alcohol per day suffered from a significant increase in risk of AAC. Subgroup analyses found elderly ever and current smokers suffered from a significantly elevated AAC risk, as did middle-aged ever smokers. Elderly ever and current alcohol consumers also experienced increased risk of AAC.

Conclusions: Smoking history is significantly associated with both AAC and severe AAC. The cardiovascular benefits associated with smoking cessation primarily manifest as reduction in risk of AAC presence rather than severe AAC. Elderly smokers are exposed to a greater risk of AAC. In contrast, alcohol consumption shows no association with severe AAC. Alcohol consumption is not associated with AAC except in heavy drinking and elderly subpopulations.

背景:有关饮酒与腹主动脉钙化(AAC)之间关系的研究结果并不一致。关于吸烟和饮酒与普通中老年人群(包括年龄亚组)腹主动脉钙化的关系,目前还缺乏相关证据。本研究利用全国性调查数据来探讨这些关联:分析了2013-2014年全国健康与营养调查(NHANES)中接受双X射线吸收测量的中老年参与者的数据。AAC严重程度采用评分系统进行评估,最大值为24。AAC评分>0为存在AAC,AAC评分≥6为严重AAC。采用二元逻辑回归分析吸烟和饮酒相关指数与是否存在AAC的关系,而累积几率逻辑回归则探讨它们与严重AAC的关系:结果:分析了 3135 名参与者的数据。结果:对 3135 名参与者的数据进行了分析。对整个人群的调查发现,吸烟史与 AAC 和严重 AAC 都有关联。相比之下,饮酒史与AAC或严重AAC无关。在对混杂因素进行调整后,研究结果证实吸烟史与AAC和严重AAC有显著关联。目前的饮酒量与AAC或严重AAC均无明显关联。与从不吸烟者相比,曾经吸烟者和目前吸烟者的AAC风险更高。与当前吸烟者相比,曾经吸烟者的 AAC 风险明显较低。与从不饮酒者相比,曾经饮酒者和现在饮酒者的酒精中毒风险都不相同。曾经饮酒者和目前饮酒者的 AAC 风险没有差异。每天饮酒超过两杯的人患急性呼吸道感染的风险显著增加。分组分析发现,曾经吸烟和现在吸烟的老年人以及曾经吸烟的中年人患 AAC 的风险明显增加。曾经饮酒和目前饮酒的老年人也面临更高的AAC风险:结论:吸烟史与急性心肌梗死和严重急性心肌梗死密切相关。戒烟对心血管的益处主要体现在降低出现 AAC 的风险,而不是严重 AAC。老年吸烟者患 AAC 的风险更大。相比之下,饮酒与严重的 AAC 无关。除大量饮酒和老年人亚群外,饮酒与 AAC 无关。
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来源期刊
Reviews in cardiovascular medicine
Reviews in cardiovascular medicine 医学-心血管系统
CiteScore
2.70
自引率
3.70%
发文量
377
审稿时长
1 months
期刊介绍: RCM is an international, peer-reviewed, open access journal. RCM publishes research articles, review papers and short communications on cardiovascular medicine as well as research on cardiovascular disease. We aim to provide a forum for publishing papers which explore the pathogenesis and promote the progression of cardiac and vascular diseases. We also seek to establish an interdisciplinary platform, focusing on translational issues, to facilitate the advancement of research, clinical treatment and diagnostic procedures. Heart surgery, cardiovascular imaging, risk factors and various clinical cardiac & vascular research will be considered.
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