Retrospective Study on the Comparative Efficacy of Intra-Articular Injection and Photodynamic Therapy in the Treatment of TMD.

IF 2.8 3区医学 Q1 Pharmacology, Toxicology and Pharmaceutics

Therapeutics and Clinical Risk Management Pub Date : 2025-03-27 eCollection Date: 2025-01-01 DOI:10.2147/TCRM.S512151

Xiaotong Wei, Jing Gao, Zhizhengrong Tian, Fengyun Zhao, Hao Wang, Wei Yan

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引用次数: 0

Abstract

Objective: To compare the effectiveness of intra-articular injection and photodynamic therapy (PDT) in the treatment of temporomandibular joint disorder (TMD).

Methods: A retrospective analysis was conducted on the clinical data of 91 TMD patients admitted to our hospital from August 2022 to February 2024. Patients were divided into the control group (n=45, treated with intra-articular injection) and the observation group (n=46, treated with PDT). Clinical outcomes, pain levels [Visual Analog Scale (VAS)], maximum mouth opening, masseter muscle pain threshold, Fricton Temporomandibular Joint Index (including Joints Number (JN), Joint Pain (JP), Muscle Masseter (MM), Disc Displacement Index (DI), Mandibular Position (MP), Pain Index (PI), and Clinical Measurement Index (CMI)], oral health [Oral Health Impact Profile-14 (OHIP-14)], and quality of life [Short Form-36 (SF-36)] were compared between the two groups.

Results: The total effective rate in the observation group (91.30%) was significantly higher than the control group (75.56%) (p<0.05). VAS scores showed significant group (F=5.487), time (F=8.356), and interaction effects (F=6.931) (p<0.05). Within-group comparisons showed a significant decrease in VAS scores 1 and 4 weeks after treatment (p<0.05), with the observation group showing lower VAS scores than the control group (p<0.05). After treatment, maximum mouth opening and masseter muscle pain threshold increased in both groups, with the observation group showing greater improvement (p<0.05). Fricton Temporomandibular Joint Index scores decreased significantly in both groups, with the observation group showing a more significant reduction (p<0.05). OHIP-14 scores decreased, and SF-36 scores increased in both groups, with the observation group showing greater improvement (p<0.05).

Conclusion: PDT is more effective than intra-articular injection in treating TMD. PDT further relieves pain, increases maximum mouth opening and masseter muscle pain threshold, reduces the Fricton index, and improves oral health and quality of life.

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关节内注射与光动力治疗TMD疗效比较的回顾性研究。

目的：比较关节内注射和光动力疗法（PDT）治疗颞下颌关节紊乱（TMD）的疗效。方法：对我院2022年8月至2024年2月收治的91例TMD患者的临床资料进行回顾性分析。将患者分为对照组（45例，关节内注射治疗）和观察组（46例，PDT治疗）。比较两组患者的临床结局、疼痛水平[视觉模拟量表（VAS）]、最大张口度、咬肌疼痛阈值、摩擦颞下颌关节指数（包括关节数（JN）、关节疼痛（JP）、咬肌（MM）、椎间盘移位指数（DI）、下颌位置（MP）、疼痛指数（PI）和临床测量指数（CMI））、口腔健康状况[口腔健康影响概况-14 (o髋关节-14)]和生活质量[SF-36]。结果：观察组总有效率（91.30%）显著高于对照组（75.56%）。结论：PDT治疗TMD的疗效优于关节内注射。PDT进一步缓解疼痛，增加最大张嘴和咬肌疼痛阈值，降低Fricton指数，改善口腔健康和生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Therapeutics and Clinical Risk Management HEALTH CARE SCIENCES & SERVICES-

CiteScore

5.30

自引率

3.60%

发文量

139

审稿时长

16 weeks

期刊介绍： Therapeutics and Clinical Risk Management is an international, peer-reviewed journal of clinical therapeutics and risk management, focusing on concise rapid reporting of clinical studies in all therapeutic areas, outcomes, safety, and programs for the effective, safe, and sustained use of medicines, therapeutic and surgical interventions in all clinical areas. The journal welcomes submissions covering original research, clinical and epidemiological studies, reviews, guidelines, expert opinion and commentary. The journal will consider case reports but only if they make a valuable and original contribution to the literature. As of 18th March 2019, Therapeutics and Clinical Risk Management will no longer consider meta-analyses for publication. The journal does not accept study protocols, animal-based or cell line-based studies.