Firing rate distributions in plastic networks of spiking neurons.

Abstract

In recurrent networks of leaky integrate-and-fire neurons, the mean-field theory has been instrumental in capturing the statistical properties of neuronal activity, like firing rate distributions. This theory has been applied to networks with either homogeneous synaptic weights and heterogeneous connections per neuron or vice versa. Our work expands mean-field models to include networks with both types of structural heterogeneity simultaneously, particularly focusing on those with synapses that undergo plastic changes. The model introduces a spike trace for each neuron, a variable that rises with neuron spikes and decays without activity, influenced by a degradation rate r _p and the neuron's firing rate ν. When the ratio α = ν/r _p is significantly high, this trace effectively estimates the neuron's firing rate, allowing synaptic weights at equilibrium to be determined by the firing rates of connected neurons. This relationship is incorporated into our mean-field formalism, providing exact solutions for firing rate and synaptic weight distributions at equilibrium in the high α regime. However, the model remains accurate within a practical range of degradation rates, as demonstrated through simulations with networks of excitatory and inhibitory neurons. This approach sheds light on how plasticity modulates both activity and structure within neuronal networks, offering insights into their complex behavior.