Premature mortality due to diabetes in Japan: a nationwide analysis from 2000 to 2020.

IF 1.3 Q4 ENDOCRINOLOGY & METABOLISM

Diabetology International Pub Date : 2025-02-02 eCollection Date: 2025-04-01 DOI:10.1007/s13340-025-00801-5

Duc-Cuong Le, Truong-Minh Pham, Pham Nguyen Quy, Aki Kondo, Thi Thu Huong Le, Alysha Crocker, Narender Singh, Tatsuhiko Kubo, Yoshihisa Fujino, Shinya Matsuda

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引用次数: 0

Abstract

Aims: We examined if there has been improvements in the lifespan of people who died from diabetes in Japan between 2000 and 2020 using the novel average lifespan shortened (ALSS) measure.

Methods: The number of deaths due to diabetes in Japan were obtained from the World Health Organization mortality database. We calculated age standardized rates (ASR) using direct method adjusted to the World Standard Population. Years of life lost (YLL) due to diabetes was calculated using Japanese life tables. ALSS measure was calculated as a ratio of YLL to the expected lifespan. We used the bootstrap method to calculate 95% confidence interval (95% CI) for the ALSS measure.

Results: The ASR of deaths due to diabetes decreased from 5.5 to 3.7 deaths per 100,000 people in men, and from 2.9 to 1.5 deaths in women over the study period. The ALSS results show that men with diabetes lost 18.0% (95% CI 17.7-18.3) of their lifespan at the beginning of the study period, but only 14.3% (95% CI 14.1-14.6) of their lifespan at the end of the study period. Similarly, the ALSS values for women decreased from 15.0% (95% CI 14.7-15.2) of their lifespan to 12.1% (95% CI 11.9-12.3) at the end of the study period.

Conclusion: Results from the new ALSS measure show lifespan of people who died from diabetes prolonged by about 4 and 3 percentage points in men and women over the study.

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日本糖尿病导致的过早死亡：2000年至2020年的全国分析。

目的：我们采用新的平均寿命缩短（ALSS）测量方法，研究了2000年至2020年间日本因糖尿病死亡者的寿命是否有所改善：日本因糖尿病死亡的人数来自世界卫生组织的死亡数据库。我们采用直接法计算了年龄标准化率（ASR），并根据世界标准人口进行了调整。糖尿病导致的寿命损失年数（YLL）是通过日本生命表计算得出的。ALSS测量值按YLL与预期寿命之比计算。我们使用引导法计算了ALSS指标的95%置信区间（95% CI）：在研究期间，男性因糖尿病死亡的 ASR 从每 10 万人中 5.5 例降至 3.7 例，女性从 2.9 例降至 1.5 例。ALSS 结果显示，在研究初期，男性糖尿病患者的寿命减少了 18.0%（95% CI 17.7-18.3），但在研究期末，他们的寿命只减少了 14.3%（95% CI 14.1-14.6）。同样，女性的 ALSS 值也从占其寿命的 15.0% (95% CI 14.7-15.2) 降至研究期结束时的 12.1% (95% CI 11.9-12.3)：新的ALSS测量结果显示，在研究期间，死于糖尿病的男性和女性寿命分别延长了约4个百分点和3个百分点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diabetology International ENDOCRINOLOGY & METABOLISM-

CiteScore

3.90

自引率

4.50%

发文量

期刊介绍： Diabetology International, the official journal of the Japan Diabetes Society, publishes original research articles about experimental research and clinical studies in diabetes and related areas. The journal also presents editorials, reviews, commentaries, reports of expert committees, and case reports on any aspect of diabetes. Diabetology International welcomes submissions from researchers, clinicians, and health professionals throughout the world who are interested in research, treatment, and care of patients with diabetes. All manuscripts are peer-reviewed to assure that high-quality information in the field of diabetes is made available to readers. Manuscripts are reviewed with due respect for the author''s confidentiality. At the same time, reviewers also have rights to confidentiality, which are respected by the editors. The journal follows a single-blind review procedure, where the reviewers are aware of the names and affiliations of the authors, but the reviewer reports provided to authors are anonymous. Single-blind peer review is the traditional model of peer review that many reviewers are comfortable with, and it facilitates a dispassionate critique of a manuscript.