Postal dosimetry audit for scanning proton beam using radiophotoluminescence glass dosimeter: A multicenter pilot study.

Medical physics Pub Date : 2025-03-29 DOI:10.1002/mp.17790
Keisuke Yasui, Miuna Hayashi, Shiryu Otsuka, Toshiyuki Toshito, Chihiro Omachi, Masaya Ichihara, Riki Oshika, Yuki Tominaga, Hiromi Baba, Hidetoshi Shimizu, Naoki Hayashi
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Abstract

Background: Accurate dosimetry is important in radiotherapy, and all equipment used for radiotherapy shoud be audited by an independent external dose audit. Radiophotoluminescence glass dosimeter (RPLD) has excellent characteristics and is widely used for postal dose audit; however, postal dose audit for proton therapy using RPLD has not been established.

Purpose: This study aims to develop a postal dose audit procedure for scanning proton beams using RPLD, estimate uncertainties, and conduct a multicenter pilot study to validate the methodology.

Methods: A postal toolkit was developed and a postal dose audit procedure for RPLD measurements of scanning proton beams was established in cooperation with several facilities that employ various accelerators, irradiation equipment, and treatment planning systems (TPS) for clinical use. Based on basic and previous studies, an uncertainty budget was developed for estimating relative uncertainty and pilot studies were conducted at each site. A method for postal dose audits was developed in a multicenter collaboration to develop an approach suitable for implementation across multiple facilities.

Results: The relative response of 60 RPLDs for scanning proton beam examined in this study was 1.00 ± 1.28% mean ± standard deviation. The combined relative standard uncertainty of postal dosimetry for scanning proton beams using the RPLD was 2.97% (k = 1). Under the reference condition, the maximum differences between the ionization chamber measurement (IC) and TPS, RPLD and TPS, and RPLD and IC were 0.97, 1.88, and 2.12%, respectively. The maximum differences between the RPLD and ionization chamber for plateau measurements at 3 cm depth using single-energy and non-reference conditions were 11.31 and 4.02%, respectively.

Conclusion: We established a procedure for the postal dose audits of proton beams using RPLD and presented the results of a multicenter pilot study. By standardizing the reference conditions, the dosimetry uncertainty was estimated at 2.92%. The results demonstrated the feasibility of performing an independent third-party dose audit of scanning proton beams using RPLD, and for such postal dose audits for proton beams, the irradiation conditions should be standardized to reduce uncertainties. These results are expected to contribute to the development of proton beams.

使用放射光致发光玻璃剂量计扫描质子束的邮政剂量学审核:一项多中心试点研究。
背景:准确的剂量测定在放射治疗中很重要,所有用于放射治疗的设备都应经过独立的外部剂量审计。辐射光致发光玻璃剂量计(RPLD)具有优良的特性,广泛用于邮政剂量审计;然而,使用RPLD的质子治疗的邮寄剂量审计尚未建立。目的:本研究旨在开发一种使用RPLD扫描质子束的邮政剂量审计程序,估计不确定性,并进行多中心试点研究来验证该方法。方法:与使用各种加速器、辐照设备和临床治疗计划系统(TPS)的几家机构合作,开发了一个邮政工具包,并建立了扫描质子束RPLD测量的邮政剂量审计程序。在基础研究和以往研究的基础上,制定了一个不确定性预算,用于估算相对不确定性,并在每个站点进行了试点研究。在多中心合作中开发了一种邮政剂量审计方法,以开发适合跨多个设施实施的方法。结果:60个rpld对扫描质子束的相对响应为1.00±1.28%(平均±标准差)。在参考条件下,电离室测量(IC)与TPS、RPLD与TPS、RPLD与IC的最大差异分别为0.97、1.88和2.12%。在单能量和非参考条件下,RPLD与电离室在3 cm深度平台测量的最大差异分别为11.31%和4.02%。结论:我们建立了一种使用RPLD进行质子束邮政剂量审计的程序,并提出了一项多中心试点研究的结果。通过标准化标准条件,估计剂量学不确定度为2.92%。结果表明,使用RPLD对扫描质子束进行独立的第三方剂量审计是可行的,对于这种质子束的邮政剂量审计,应标准化辐照条件以减少不确定性。这些结果有望对质子束的发展作出贡献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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