{"title":"SIRI+Q model with a limited capacity of isolation.","authors":"Zhiqiong Fu, Hiromi Seno","doi":"10.1007/s12064-025-00437-8","DOIUrl":null,"url":null,"abstract":"<p><p>We construct and analyze an SIRI+Q model with a piecewise smooth system of ordinary differential equations for the epidemic dynamics of a reinfectious disease, in which a limited capacity of isolation is incorporated. To consider the relation of the limited isolation capacity to the epidemic consequence, we derive the condition that the isolation reaches the capacity at finite time along the path of the epidemic process, and that the disease becomes endemic. We investigate in particular how the endemicity, the endemic size, or the final epidemic size could depend on the isolation capacity. From the obtained mathematical results, we find theoretical implications on the relevance of the isolation capacity and the difficulty of its measure to control the spread of the disease in the community.</p>","PeriodicalId":54428,"journal":{"name":"Theory in Biosciences","volume":" ","pages":""},"PeriodicalIF":1.3000,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Theory in Biosciences","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1007/s12064-025-00437-8","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
We construct and analyze an SIRI+Q model with a piecewise smooth system of ordinary differential equations for the epidemic dynamics of a reinfectious disease, in which a limited capacity of isolation is incorporated. To consider the relation of the limited isolation capacity to the epidemic consequence, we derive the condition that the isolation reaches the capacity at finite time along the path of the epidemic process, and that the disease becomes endemic. We investigate in particular how the endemicity, the endemic size, or the final epidemic size could depend on the isolation capacity. From the obtained mathematical results, we find theoretical implications on the relevance of the isolation capacity and the difficulty of its measure to control the spread of the disease in the community.
期刊介绍:
Theory in Biosciences focuses on new concepts in theoretical biology. It also includes analytical and modelling approaches as well as philosophical and historical issues. Central topics are:
Artificial Life;
Bioinformatics with a focus on novel methods, phenomena, and interpretations;
Bioinspired Modeling;
Complexity, Robustness, and Resilience;
Embodied Cognition;
Evolutionary Biology;
Evo-Devo;
Game Theoretic Modeling;
Genetics;
History of Biology;
Language Evolution;
Mathematical Biology;
Origin of Life;
Philosophy of Biology;
Population Biology;
Systems Biology;
Theoretical Ecology;
Theoretical Molecular Biology;
Theoretical Neuroscience & Cognition.