Pollution in marine bivalves: The immunosuppressive effects of microplastics on Anadara granosa

IF 3 3区环境科学与生态学 Q2 ENVIRONMENTAL SCIENCES

Marine environmental research Pub Date : 2025-03-28 DOI:10.1016/j.marenvres.2025.107107

Siyi Huang , Hejian Li , Lixue Zhao , Yu Han , Hongxing Liu , Shanjie Zha , Yongbo Bao

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Abstract

Microplastics (MPs), as emerging marine pollutants, pose a significant threat to marine organisms and ecosystems. This study investigates the effects of 7-day MPs exposure on the immune response of the blood clam (Anadara granosa), a commercially valuable marine bivalve known for its filter-feeding and sedentary lifestyle, which renders it particularly vulnerable to pollutants. This study analyzed the impact of various concentrations (0, 0.1, 1, and 10 mg/L) of polystyrene MPs (PS MPs) on the immune response of blood clam hemocytes, focusing on the mechanisms of immunotoxicity, including changes in hemoglobin content, reactive oxygen species levels, cell viability, and the expression of immune-related genes. The findings indicate that a one-week exposure to PS MPs significantly compromised the immune response of blood clam hemocytes, exhibiting a pronounced dose-dependent relationship. There was a significant reduction in the total hemocyte count, concentration of hemoglobin, lysozyme content, and activity following PS MPs exposure. Additionally, the levels of calcium ions, the activities of acid and alkaline phosphatases varied with the concentration of PS MPs, suggesting that increased PS MPs concentrations suppress the immune activity of blood clams. This suppression could diminish their capacity to fend off external aggressions and heighten the risk of disease outbreaks. The study provides novel insights into the impact of PS MPs on the immune response of marine bivalves and lays the groundwork for further ecotoxicological research.

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来源期刊

Marine environmental research 环境科学-毒理学

CiteScore

5.90

自引率

3.00%

发文量

217

审稿时长

46 days

期刊介绍： Marine Environmental Research publishes original research papers on chemical, physical, and biological interactions in the oceans and coastal waters. The journal serves as a forum for new information on biology, chemistry, and toxicology and syntheses that advance understanding of marine environmental processes. Submission of multidisciplinary studies is encouraged. Studies that utilize experimental approaches to clarify the roles of anthropogenic and natural causes of changes in marine ecosystems are especially welcome, as are those studies that represent new developments of a theoretical or conceptual aspect of marine science. All papers published in this journal are reviewed by qualified peers prior to acceptance and publication. Examples of topics considered to be appropriate for the journal include, but are not limited to, the following: – The extent, persistence, and consequences of change and the recovery from such change in natural marine systems – The biochemical, physiological, and ecological consequences of contaminants to marine organisms and ecosystems – The biogeochemistry of naturally occurring and anthropogenic substances – Models that describe and predict the above processes – Monitoring studies, to the extent that their results provide new information on functional processes – Methodological papers describing improved quantitative techniques for the marine sciences.