The association between body temperature and 28-day mortality in sepsis patients: A retrospective observational study

IF 2.7 4区医学 Q2 CRITICAL CARE MEDICINE

Medicina Intensiva Pub Date : 2025-04-01 DOI:10.1016/j.medin.2024.08.011

Wei Yang , Dan Zhou , Hui Peng , Huilin Jiang , Weifeng Chen

引用次数: 0

Abstract

Objective

This study explored the association between body temperature and 28-day septic ICU hospital mortality.

Design

Retrospective cohort analysis.

Setting

208 ICUs in the United States.

Patients or participants

Sepsis patients from 2014–2015 eICU Collaborative Research Database.

Interventions

Binary logistic regression models, Generalized Additive Model (GAM), Two-Piece Binary Logistic Regression Model.

Main variables of interest

Body temperature, 28-day inpatient mortality.

Results

Nonlinear relationship observed; hypothermia (≤36.67 ℃) associated with increased mortality (adjusted OR = 0.74, 95% CI: 0.70–0.80, p < 0.0001).

Conclusions

Hypothermia in sepsis correlates with higher mortality; rewarming's potential benefit warrants further exploration.

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败血症患者体温与28天死亡率之间的关系：一项回顾性观察性研究

目的探讨体温与感染性重症监护室住院28天死亡率的关系。设计回顾性队列分析。在美国设置208个icu。患者或参与者2014-2015年eICU合作研究数据库中的脓毒症患者。干预：二元logistic回归模型，广义加性模型（GAM），二件二元logistic回归模型。主要感兴趣的变量体温，28天住院死亡率。结果观察到非线性关系；低温（≤36.67 ℃）与死亡率增加相关（调整后比值 = 0.74,95% CI: 0.70-0.80, p <； 0.0001）。结论败血症患者体温升高与死亡率增高有关；气候变暖的潜在好处值得进一步探索。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medicina Intensiva CRITICAL CARE MEDICINE-

CiteScore

2.70

自引率

20.00%

发文量

146

审稿时长

33 days

期刊介绍： Medicina Intensiva is the journal of the Spanish Society of Intensive Care Medicine and Coronary Units (SEMICYUC) and of Pan American and Iberian Federation of Societies of Intensive and Critical Care Medicine. Medicina Intensiva has become the reference publication in Spanish in its field. The journal mainly publishes Original Articles, Reviews, Clinical Notes, Consensus Documents, Images, and other information relevant to the specialty. All works go through a rigorous selection process. The journal accepts submissions of articles in English and in Spanish languages. The journal follows the publication requirements of the International Committee of Medical Journal Editors (ICMJE) and the Committee on Publication Ethics (COPE).