{"title":"Advances in Single-Molecule Electrical Transport Studies of Peptides","authors":"Cunxin Han, Chao Chen, Hanqing Shi, Wenzhe Chen, Wei Sun, Bing Li","doi":"10.1039/d5cp00128e","DOIUrl":null,"url":null,"abstract":"The charge transport between peptide molecules is one of the crucial factors sustaining various biochemical processes within biological organisms. Understanding the charge transport processes between peptide molecules is of great significance for further investigating life reaction processes. Through single-molecule electronics characterization techniques, we have reviewed the effects of the structure of peptide molecules and external experimental factors on their charge transport. Additionally, we have summarized the latest research on supramolecular interactions between peptide chains, particularly focusing on the even-odd effect. This not only enhances our understanding of the charge transport mechanisms between peptide molecules but lays a solid theoretical foundation for the widespread application of peptide molecules in fields such as biological devices.","PeriodicalId":99,"journal":{"name":"Physical Chemistry Chemical Physics","volume":"40 1","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physical Chemistry Chemical Physics","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d5cp00128e","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
Abstract
The charge transport between peptide molecules is one of the crucial factors sustaining various biochemical processes within biological organisms. Understanding the charge transport processes between peptide molecules is of great significance for further investigating life reaction processes. Through single-molecule electronics characterization techniques, we have reviewed the effects of the structure of peptide molecules and external experimental factors on their charge transport. Additionally, we have summarized the latest research on supramolecular interactions between peptide chains, particularly focusing on the even-odd effect. This not only enhances our understanding of the charge transport mechanisms between peptide molecules but lays a solid theoretical foundation for the widespread application of peptide molecules in fields such as biological devices.
期刊介绍:
Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions.
The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.