Editorial expression of concern: Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase-ceramide cascade mediated by synergistic activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase

Abstract

Correction: Mol Cancer 9, 239 (2010)

https://doi.org/10.1186/1476-4598-9-239

The Editor-in-Chief is issuing this editorial expression of concern to inform the readers that following the publication of the article, concerns were raised regarding multiple image similarities found in Figs. 1B and E and 2C, 3 A, 4 A, 5 A, and 7E. Due to the age of the article, the authors were unable to provide all concerned raw data files. An investigation by the publisher found evidence of image editing that was not transparently stated in the article. Additionally, the flow cytometry plot in Fig. 1e shows repetitive data point patterns, which are unlikely to occur naturally in this type of data. Similarly, the background of the blot presented in Fig. 2c appears to show repetitive non-specific markings.

Therefore readers are alerted to interpret this data with caution.

Author, Chitra Mandal agrees with this Editorial Express of Concern. The Publisher is unable to get current email addresses for authors, Susmita Mondal, Chandan Mandal, Rajender Sangwan, and Sarmila Chandra.

Authors and Affiliations

1. Infectious diseases and immunology Division, Indian Institute of Chemical Biology, A Unit of Council of Scientific and Industrial Research, Govt. of India, 4, Raja S. C. Mullick Road, Kolkata, 700032, India

   Susmita Mondal, Chandan Mandal & Chitra Mandal

2. Central Institute of Medicinal and Aromatic Plants, Lucknow, 226015, India

   Rajender Sangwan

3. Kothari Medical Center, 8/3, Alipore Road, Kolkata, 700027, India

   Sarmila Chandra

4. Department of Microbiology, Sammilani Mahavidyalaya, Baghajatin, E.M By Pass, Kolkata, 700075, India

   Susmita Mondal

Authors

1. Susmita MondalView author publications

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2. Chandan MandalView author publications

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3. Rajender SangwanView author publications

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4. Sarmila ChandraView author publications

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5. Chitra MandalView author publications

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Corresponding author

Correspondence to Chitra Mandal.

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Mondal, S., Mandal, C., Sangwan, R. et al. Editorial expression of concern: Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase-ceramide cascade mediated by synergistic activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase. Mol Cancer 24, 103 (2025). https://doi.org/10.1186/s12943-024-02185-7

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• Published: 31 March 2025

• DOI: https://doi.org/10.1186/s12943-024-02185-7

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