Utility of Cardiac CT for Cardiomyopathy Phenotyping.

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Tomography Pub Date : 2025-03-20 DOI:10.3390/tomography11030039

Ramzi Ibrahim, Mahmoud Abdelnabi, Girish Pathangey, Juan Farina, Steven J Lester, Chadi Ayoub, Said Alsidawi, Balaji K Tamarappoo, Clinton Jokerst, Reza Arsanjani

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引用次数: 0

Abstract

Cardiac computed tomography (CT) has rapidly advanced, becoming an invaluable tool for diagnosing and prognosticating various cardiovascular diseases. While echocardiography and cardiac magnetic resonance imaging (CMR) remain the gold standards for myocardial assessment, modern CT technologies offer enhanced spatial resolution, making it an essential tool in clinical practice. Cardiac CT has expanded beyond coronary artery disease evaluation, now playing a key role in assessing cardiomyopathies and structural heart diseases. Innovations like photon-counting CT enable precise estimation of myocardial extracellular volume, facilitating the detection of infiltrative disorders and myocardial fibrosis. Additionally, CT-based myocardial strain analysis allows for the classification of impaired myocardial contractility, while quantifying cardiac volumes and function remains crucial in cardiomyopathy evaluation. This review explores the emerging role of cardiac CT in cardiomyopathy phenotyping, emphasizing recent technological advancements.

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心脏计算机断层扫描（CT）技术发展迅速，已成为诊断和预测各种心血管疾病的重要工具。虽然超声心动图和心脏磁共振成像（CMR）仍然是心肌评估的黄金标准，但现代 CT 技术提供了更高的空间分辨率，使其成为临床实践中的重要工具。心脏 CT 的应用范围已超出冠状动脉疾病评估，目前在评估心肌病和结构性心脏病方面发挥着重要作用。光子计数 CT 等创新技术可精确估算心肌细胞外容积，有助于检测浸润性疾病和心肌纤维化。此外，基于 CT 的心肌应变分析可对受损的心肌收缩力进行分类，而量化心脏体积和功能仍是心肌病评估的关键。这篇综述探讨了心脏 CT 在心肌病表型分析中的新兴作用，强调了最近的技术进步。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tomography Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

2.70

自引率

10.50%

发文量

222

期刊介绍： TomographyTM publishes basic (technical and pre-clinical) and clinical scientific articles which involve the advancement of imaging technologies. Tomography encompasses studies that use single or multiple imaging modalities including for example CT, US, PET, SPECT, MR and hyperpolarization technologies, as well as optical modalities (i.e. bioluminescence, photoacoustic, endomicroscopy, fiber optic imaging and optical computed tomography) in basic sciences, engineering, preclinical and clinical medicine. Tomography also welcomes studies involving exploration and refinement of contrast mechanisms and image-derived metrics within and across modalities toward the development of novel imaging probes for image-based feedback and intervention. The use of imaging in biology and medicine provides unparalleled opportunities to noninvasively interrogate tissues to obtain real-time dynamic and quantitative information required for diagnosis and response to interventions and to follow evolving pathological conditions. As multi-modal studies and the complexities of imaging technologies themselves are ever increasing to provide advanced information to scientists and clinicians. Tomography provides a unique publication venue allowing investigators the opportunity to more precisely communicate integrated findings related to the diverse and heterogeneous features associated with underlying anatomical, physiological, functional, metabolic and molecular genetic activities of normal and diseased tissue. Thus Tomography publishes peer-reviewed articles which involve the broad use of imaging of any tissue and disease type including both preclinical and clinical investigations. In addition, hardware/software along with chemical and molecular probe advances are welcome as they are deemed to significantly contribute towards the long-term goal of improving the overall impact of imaging on scientific and clinical discovery.