Long-term outcome of fat grafting to treat facial Systemic Sclerosis: a prospective cohort study.

IF 3.2 2区医学 Q1 SURGERY

Plastic and reconstructive surgery Pub Date : 2025-03-25 DOI:10.1097/PRS.0000000000012111

Aurora Almadori, Michelle Griffin, Jeon Hyun, Esther Hansen, Christopher P Denton, Peter Em Butler

{"title":"Long-term outcome of fat grafting to treat facial Systemic Sclerosis: a prospective cohort study.","authors":"Aurora Almadori, Michelle Griffin, Jeon Hyun, Esther Hansen, Christopher P Denton, Peter Em Butler","doi":"10.1097/PRS.0000000000012111","DOIUrl":null,"url":null,"abstract":"Background: Systemic Sclerosis (SSc) is characterized by subcutaneous tissue loss and dermal fibrosis, with limited facial movement and mouth opening. Fat grafting is a minimally invasive technique used to restore facial volume and improve skin fibrosis.Materials and methods: A cohort of 93 patients were assessed using 3D imaging (3dMD) before and after fat grafting. Secondary outcomes included physician-based assessment, mouth function (MHISS), psychological status, quality of life (DAS, HADS, VAS, BFNES), and patient-based satisfaction.Results: After an average of 2.96 (±2.2) sessions of fat grafting, with an injection volume of 11.9 cc (±6) in each session, the overall retention rate was 53.1% (±0.17) at an average follow-up of 3.11 (±1.73) years. Patients undergoing 5+ interventions presented a higher retention rate (73.1% ±0.08%) than those receiving one or two treatments (45.2% ±0.09 and 50.5% ±0.15 respectively) (P<0.05). Significant improvements were found in mouth function (P<0.0001) and quality of life (P<0.0001).Conclusion: Facial fat grafting is an effective technique for restoring facial volume and improving oral function and quality of life in patients with scleroderma. This study presents the largest number of patients published to date with the longest follow-up period.","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":""},"PeriodicalIF":3.2000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plastic and reconstructive surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/PRS.0000000000012111","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"SURGERY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Systemic Sclerosis (SSc) is characterized by subcutaneous tissue loss and dermal fibrosis, with limited facial movement and mouth opening. Fat grafting is a minimally invasive technique used to restore facial volume and improve skin fibrosis.

Materials and methods: A cohort of 93 patients were assessed using 3D imaging (3dMD) before and after fat grafting. Secondary outcomes included physician-based assessment, mouth function (MHISS), psychological status, quality of life (DAS, HADS, VAS, BFNES), and patient-based satisfaction.

Results: After an average of 2.96 (±2.2) sessions of fat grafting, with an injection volume of 11.9 cc (±6) in each session, the overall retention rate was 53.1% (±0.17) at an average follow-up of 3.11 (±1.73) years. Patients undergoing 5+ interventions presented a higher retention rate (73.1% ±0.08%) than those receiving one or two treatments (45.2% ±0.09 and 50.5% ±0.15 respectively) (P<0.05). Significant improvements were found in mouth function (P<0.0001) and quality of life (P<0.0001).

Conclusion: Facial fat grafting is an effective technique for restoring facial volume and improving oral function and quality of life in patients with scleroderma. This study presents the largest number of patients published to date with the longest follow-up period.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Plastic and reconstructive surgery 医学-外科

CiteScore

5.00

自引率

13.90%

发文量

1436

审稿时长

1.5 months

期刊介绍： For more than 70 years Plastic and Reconstructive Surgery® has been the one consistently excellent reference for every specialist who uses plastic surgery techniques or works in conjunction with a plastic surgeon. Plastic and Reconstructive Surgery® , the official journal of the American Society of Plastic Surgeons, is a benefit of Society membership, and is also available on a subscription basis. Plastic and Reconstructive Surgery® brings subscribers up-to-the-minute reports on the latest techniques and follow-up for all areas of plastic and reconstructive surgery, including breast reconstruction, experimental studies, maxillofacial reconstruction, hand and microsurgery, burn repair, cosmetic surgery, as well as news on medicolegal issues. The cosmetic section provides expanded coverage on new procedures and techniques and offers more cosmetic-specific content than any other journal. All subscribers enjoy full access to the Journal''s website, which features broadcast quality videos of reconstructive and cosmetic procedures, podcasts, comprehensive article archives dating to 1946, and additional benefits offered by the newly-redesigned website.