The Association Between Poor Sleep Quality and Lipid Levels Among Dyslipidemia Patients in Thailand: A Prospective Cross-Sectional Study.

IF 2.4 4区 医学 Q2 HEALTH CARE SCIENCES & SERVICES
Jakkrit Pintacom, Suphawita Pliannuom, Nida Buawangpong, Chaisiri Angkurawaranon, Kanokporn Pinyopornpanish
{"title":"The Association Between Poor Sleep Quality and Lipid Levels Among Dyslipidemia Patients in Thailand: A Prospective Cross-Sectional Study.","authors":"Jakkrit Pintacom, Suphawita Pliannuom, Nida Buawangpong, Chaisiri Angkurawaranon, Kanokporn Pinyopornpanish","doi":"10.3390/healthcare13060678","DOIUrl":null,"url":null,"abstract":"<p><p><b>Background:</b> Dyslipidemia increases cardiometabolic risk, but the impact of sleep quality on lipid levels remains uncertain. This study aims to assess the prevalence of poor sleep quality in patients with dyslipidemia and its association with lipid levels. <b>Methods:</b> A cross-sectional and prospective study was conducted among patients aged 20 years and older who were diagnosed with dyslipidemia at the Family Medicine Outpatient Clinic in Thailand from July to December 2023. Data were collected through interviews and a review of electronic health records. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Blood levels of triglycerides, HDL-C, and LDL-C were measured. The association between sleep quality and lipid levels was analyzed using multivariable regression, adjusting for age, sex, body mass index, diabetes mellitus, hypertension, alcohol use, exercise, statins, fibrates, and ezetimibe. <b>Results:</b> Of the 257 participants, 183 (71.21%) were female, with a mean age of 69.31 ± 7.48 years. Overall, 86 participants (33.64%) reported poor sleep quality. A higher sum score of PSQI was significantly associated with elevated triglyceride levels (adjusted mean difference [AMD] 2.59, 95% CI 0.07-5.11, <i>p</i> = 0.044), particularly in the sleep latency domain (AMD 8.58, 95% CI 0.00-17.16, <i>p</i> = 0.050). Additionally, higher scores in the subjective sleep quality domain were significantly associated with increased LDL-C levels (AMD 8.08, 95% CI 1.70-14.60, <i>p</i> = 0.013). <b>Conclusions:</b> This study highlights a significant association between poor sleep quality and elevated triglyceride and LDL-C levels. These findings underscore the importance of integrated healthcare strategies that address both sleep quality and lipid management to mitigate cardiovascular risks.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"13 6","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11941784/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Healthcare","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/healthcare13060678","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Dyslipidemia increases cardiometabolic risk, but the impact of sleep quality on lipid levels remains uncertain. This study aims to assess the prevalence of poor sleep quality in patients with dyslipidemia and its association with lipid levels. Methods: A cross-sectional and prospective study was conducted among patients aged 20 years and older who were diagnosed with dyslipidemia at the Family Medicine Outpatient Clinic in Thailand from July to December 2023. Data were collected through interviews and a review of electronic health records. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Blood levels of triglycerides, HDL-C, and LDL-C were measured. The association between sleep quality and lipid levels was analyzed using multivariable regression, adjusting for age, sex, body mass index, diabetes mellitus, hypertension, alcohol use, exercise, statins, fibrates, and ezetimibe. Results: Of the 257 participants, 183 (71.21%) were female, with a mean age of 69.31 ± 7.48 years. Overall, 86 participants (33.64%) reported poor sleep quality. A higher sum score of PSQI was significantly associated with elevated triglyceride levels (adjusted mean difference [AMD] 2.59, 95% CI 0.07-5.11, p = 0.044), particularly in the sleep latency domain (AMD 8.58, 95% CI 0.00-17.16, p = 0.050). Additionally, higher scores in the subjective sleep quality domain were significantly associated with increased LDL-C levels (AMD 8.08, 95% CI 1.70-14.60, p = 0.013). Conclusions: This study highlights a significant association between poor sleep quality and elevated triglyceride and LDL-C levels. These findings underscore the importance of integrated healthcare strategies that address both sleep quality and lipid management to mitigate cardiovascular risks.

泰国血脂异常患者睡眠质量差与血脂水平之间的关系:一项前瞻性横断面研究。
背景:血脂异常会增加心脏代谢风险,但睡眠质量对血脂水平的影响仍不确定。本研究旨在评估血脂异常患者睡眠质量差的患病率及其与血脂水平的关系。方法:对2023年7月至12月在泰国家庭医学门诊诊断为血脂异常的20岁及以上患者进行横断面前瞻性研究。通过访谈和审查电子健康记录收集数据。采用匹兹堡睡眠质量指数(PSQI)评估睡眠质量。测量血液中甘油三酯、HDL-C和LDL-C的水平。采用多变量回归分析睡眠质量和脂质水平之间的关系,调整年龄、性别、体重指数、糖尿病、高血压、饮酒、运动、他汀类药物、贝特类药物和依折替米。结果:257例患者中,女性183例(71.21%),平均年龄69.31±7.48岁。总体而言,86名参与者(33.64%)报告睡眠质量差。PSQI总评分较高与甘油三酯水平升高显著相关(校正平均差[AMD] 2.59, 95% CI 0.07-5.11, p = 0.044),特别是在睡眠潜伏期域(AMD 8.58, 95% CI 0.00-17.16, p = 0.050)。此外,主观睡眠质量得分越高,LDL-C水平越高(AMD为8.08,95% CI为1.70-14.60,p = 0.013)。结论:本研究强调了睡眠质量差与甘油三酯和LDL-C水平升高之间的显著关联。这些发现强调了解决睡眠质量和脂质管理以降低心血管风险的综合医疗保健策略的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Healthcare
Healthcare Medicine-Health Policy
CiteScore
3.50
自引率
7.10%
发文量
0
审稿时长
47 days
期刊介绍: Healthcare (ISSN 2227-9032) is an international, peer-reviewed, open access journal (free for readers), which publishes original theoretical and empirical work in the interdisciplinary area of all aspects of medicine and health care research. Healthcare publishes Original Research Articles, Reviews, Case Reports, Research Notes and Short Communications. We encourage researchers to publish their experimental and theoretical results in as much detail as possible. For theoretical papers, full details of proofs must be provided so that the results can be checked; for experimental papers, full experimental details must be provided so that the results can be reproduced. Additionally, electronic files or software regarding the full details of the calculations, experimental procedure, etc., can be deposited along with the publication as “Supplementary Material”.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信