Innovative smart biosensors for cancer theranostics: A new frontier in detection, diagnosis, and beyond

Q3 Medicine

Cancer treatment and research communications Pub Date : 2025-01-01 DOI:10.1016/j.ctarc.2025.100911

Archna Dhasmana , Ayushi Santhanam , Khushi Dhasmana , Sumira Malik , Subham Preetam

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引用次数: 0

Abstract

Cancer is still a major health concern worldwide, requiring ongoing improvements in methods of diagnosis and treatment. During the past decade, smart biosensors have become essential instruments in cancer theranostics, improving diagnosis accuracy, tracking treatment efficacy, and customizing patient care. This review thoroughly investigates how smart biosensors have revolutionized the field of cancer. The potential of major technical advancements, such as wearable technology, microfluidic platforms, and sensors based on nanomaterials to identify cancer biomarkers with high sensitivity and specificity is investigated. A detailed discussion is held regarding clinical applications that include early diagnosis, real-time monitoring of therapy responses, and support for personalized medicine techniques. Future directions targeted at optimizing the therapeutic utility of smart biosensors in oncology are also examined, along with issues pertaining to regulatory routes and clinical translation hurdles. This study highlights the potential of smart biosensors to transform cancer treatment, bringing in a new era of precision medicine and better patient outcomes by combining insights from multiple viewpoints.

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用于癌症治疗的创新智能生物传感器：检测、诊断及其他领域的新前沿

癌症仍然是全世界的一个主要健康问题，需要不断改进诊断和治疗方法。在过去的十年中，智能生物传感器已经成为癌症治疗中必不可少的工具，可以提高诊断准确性，跟踪治疗效果，并定制患者护理。这篇综述深入研究了智能生物传感器是如何彻底改变癌症领域的。研究了可穿戴技术、微流控平台和基于纳米材料的传感器等重大技术进步的潜力，以高灵敏度和特异性识别癌症生物标志物。详细讨论了临床应用，包括早期诊断，治疗反应的实时监测，以及对个性化医疗技术的支持。针对优化智能生物传感器在肿瘤学中的治疗效用的未来方向也进行了研究，以及与监管途径和临床翻译障碍有关的问题。这项研究强调了智能生物传感器在改变癌症治疗方面的潜力，通过结合多角度的见解，带来精准医疗的新时代和更好的患者治疗效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cancer treatment and research communications Medicine-Oncology

CiteScore

4.30

自引率

0.00%

发文量

148

审稿时长

56 days

期刊介绍： Cancer Treatment and Research Communications is an international peer-reviewed publication dedicated to providing comprehensive basic, translational, and clinical oncology research. The journal is devoted to articles on detection, diagnosis, prevention, policy, and treatment of cancer and provides a global forum for the nurturing and development of future generations of oncology scientists. Cancer Treatment and Research Communications publishes comprehensive reviews and original studies describing various aspects of basic through clinical research of all tumor types. The journal also accepts clinical studies in oncology, with an emphasis on prospective early phase clinical trials. Specific areas of interest include basic, translational, and clinical research and mechanistic approaches; cancer biology; molecular carcinogenesis; genetics and genomics; stem cell and developmental biology; immunology; molecular and cellular oncology; systems biology; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; cancer policy; and integration of various approaches. Our mission is to be the premier source of relevant information through promoting excellence in research and facilitating the timely translation of that science to health care and clinical practice.