Maternal genetic architecture of Guizhou's Hmong-Mien populations via whole mitogenome

IF 3.4 2区生物学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Genomics Pub Date : 2025-03-24 DOI:10.1016/j.ygeno.2025.111041

Li Chen , Yuhang Feng , Shuaiji Pan , Lin Wang , Hongling Zhang , Xiaoye Jin , Qiyan Wang , Yubo Liu , Meiqing Yang , Xiaolan Huang , Shunyi Tian , Changyun Gu , Jiang Huang , Zheng Ren

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引用次数: 0

Abstract

The Hmong-Mien (HM) language family, majorly distributed across southern China and Southeast Asia, has remained underexplored in population genetics, particularly concerning whole mitogenome studies. In this study, we sequenced the whole mitogenomes of 261 individuals from Guizhou Hmong-Mien-speaking populations (HM-G), comprising Miao, Yao, and She individuals. The haplogroup distribution was dominated by southern East Asian haplogroups (B, M7, and F). The neutrality test revealed significantly negative values, and mismatch distribution analyses showed a pronounced unimodal distribution, indicating high genetic diversity and recent population expansion in populations. For a comprehensive understanding of the matrilineal genetic background of the HM-speaking population, we merged whole mitogenome data from 83 populations worldwide. Our findings showed that the HM-G exhibited relatively close genetic distances to HM- and Tai-Kadai-speaking populations from East and Southeast Asia. These results provide crucial insights into the genetic structure and evolutionary history of HM-G.

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来源期刊

Genomics 生物-生物工程与应用微生物

CiteScore

9.60

自引率

2.30%

发文量

260

审稿时长

60 days

期刊介绍： Genomics is a forum for describing the development of genome-scale technologies and their application to all areas of biological investigation. As a journal that has evolved with the field that carries its name, Genomics focuses on the development and application of cutting-edge methods, addressing fundamental questions with potential interest to a wide audience. Our aim is to publish the highest quality research and to provide authors with rapid, fair and accurate review and publication of manuscripts falling within our scope.