{"title":"Evaluation of choroidal thickness in Malay children with myopia.","authors":"M Nurul-Farhana, N F Ngah, I Shatriah","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>This study aims to evaluate the choroidal thickness and its correlation with age, spherical equivalent, and axial length in Malay children with myopia, addressing the limited data available on this topic in Southeast Asia.</p><p><strong>Material and methods: </strong>A cross-sectional, hospital-based study was conducted from 2022 to 2024 at Hospital Shah Alam and Hospital Pakar Universiti Sains Malaysia. A total of 109 Malay children aged 7-17 years participated, including 88 with myopia and 21 with emmetropia. Each participant underwent a comprehensive ocular examination, including non-cycloplegic refraction and axial length measurement. Choroidal thickness was assessed using Cirrus SD-optical coherence tomography, with one eye from each subject randomly selected for analysis.</p><p><strong>Results: </strong>The mean subfoveal choroidal thickness was significantly thinner in myopic children (284.91 μm) compared to emmetropic children (347.62 μm) (p<0.001). Additionally, choroidal thickness varied significantly with the degree of myopia: mild myopia had a mean subfoveal thickness of 319.69 μm, moderate myopia 290.04 μm, and high myopia 225.72 μm, with high myopia showing the thinnest choroid (p<0.001). A significant negative correlation was observed between axial length and subfoveal choroidal thickness, while a positive correlation was found between spherical equivalent and choroidal thickness. No significant correlation was identified between age and subfoveal choroidal thickness.</p><p><strong>Conclusion: </strong>Malay children with myopia exhibit a thinner mean choroidal layer compared to their emmetropic peers, with the thinnest choroid observed in cases of high myopia. This indicates that thinning of the choroidal vasculature occurs with the increase in axial length and worsening severity of myopia.</p>","PeriodicalId":39388,"journal":{"name":"Medical Journal of Malaysia","volume":"80 2","pages":"221-227"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Journal of Malaysia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: This study aims to evaluate the choroidal thickness and its correlation with age, spherical equivalent, and axial length in Malay children with myopia, addressing the limited data available on this topic in Southeast Asia.
Material and methods: A cross-sectional, hospital-based study was conducted from 2022 to 2024 at Hospital Shah Alam and Hospital Pakar Universiti Sains Malaysia. A total of 109 Malay children aged 7-17 years participated, including 88 with myopia and 21 with emmetropia. Each participant underwent a comprehensive ocular examination, including non-cycloplegic refraction and axial length measurement. Choroidal thickness was assessed using Cirrus SD-optical coherence tomography, with one eye from each subject randomly selected for analysis.
Results: The mean subfoveal choroidal thickness was significantly thinner in myopic children (284.91 μm) compared to emmetropic children (347.62 μm) (p<0.001). Additionally, choroidal thickness varied significantly with the degree of myopia: mild myopia had a mean subfoveal thickness of 319.69 μm, moderate myopia 290.04 μm, and high myopia 225.72 μm, with high myopia showing the thinnest choroid (p<0.001). A significant negative correlation was observed between axial length and subfoveal choroidal thickness, while a positive correlation was found between spherical equivalent and choroidal thickness. No significant correlation was identified between age and subfoveal choroidal thickness.
Conclusion: Malay children with myopia exhibit a thinner mean choroidal layer compared to their emmetropic peers, with the thinnest choroid observed in cases of high myopia. This indicates that thinning of the choroidal vasculature occurs with the increase in axial length and worsening severity of myopia.
期刊介绍：
Published since 1890 this journal originated as the Journal of the Straits Medical Association. With the formation of the Malaysian Medical Association (MMA), the Journal became the official organ, supervised by an editorial board. Some of the early Hon. Editors were Mr. H.M. McGladdery (1960 - 1964), Dr. A.A. Sandosham (1965 - 1977), Prof. Paul C.Y. Chen (1977 - 1987). It is a scientific journal, published quarterly and can be found in medical libraries in many parts of the world. The Journal also enjoys the status of being listed in the Index Medicus, the internationally accepted reference index of medical journals. The editorial columns often reflect the Association''s views and attitudes towards medical problems in the country. The MJM aims to be a peer reviewed scientific journal of the highest quality. We want to ensure that whatever data is published is true and any opinion expressed important to medical science. We believe being Malaysian is our unique niche; our priority will be for scientific knowledge about diseases found in Malaysia and for the practice of medicine in Malaysia. The MJM will archive knowledge about the changing pattern of human diseases and our endeavours to overcome them. It will also document how medicine develops as a profession in the nation. We will communicate and co-operate with other scientific journals in Malaysia. We seek articles that are of educational value to doctors. We will consider all unsolicited articles submitted to the journal and will commission distinguished Malaysians to write relevant review articles. We want to help doctors make better decisions and be good at judging the value of scientific data. We want to help doctors write better, to be articulate and precise.
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