Clinical experience with the miltonia valve: short-term performance of new bi-leaflet mechanical prosthesis in mitral valve replacement surgery.

IF 0.7 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Indian Journal of Thoracic and Cardiovascular Surgery Pub Date : 2025-04-01 Epub Date: 2024-11-08 DOI:10.1007/s12055-024-01851-1

Nitin Kumar Kashyap, Pranay Mehsare, Gaind Kumar Saurabh, Nirupam Chakraborty, Subrat Singha, Minal Wasnik, Sneha Jain

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引用次数: 0

Abstract

Purpose: This study evaluates the performance of the Miltonia bi-leaflet mechanical prosthesis for mitral valve replacement (MVR).

Methodology: Fifty patients were included in this study who underwent MVR using cardiopulmonary bypass (CPB) and mild hypothermia. After surgery, standard postoperative care was provided. Echocardiography was performed preoperatively, postoperatively at discharge, and at a 6-month follow-up to assess hemodynamic performance and detect adverse events.

Results: The mean age was 38.88 ± 9.51 years, with a predominance of female patients. The average hospital stay was 9.6 ± 3.8 days. Before surgery, 88% of patients were in New York Heart Association (NYHA) class III, 8% in class IV, and 4% in class II. Post-surgery, 92% improved to class I, 4% to class II (p < 0.001). Both mean and peak pressure gradients showed significant improvement post-procedure (p < 0.001) and at 6 months (p < 0.001) compared to pre-operative status. At the 6-month follow-up, there were no cases of prosthetic valve endocarditis, structural/non-structural valve deterioration, dysfunction, or paravalvular leaks, with a 4% mortality rate. Four patients were diagnosed with prosthetic heart valve thrombosis (PHVT) during follow-up period of 6 months.

Conclusion: The Miltonia valve showed excellent hemodynamic performance and significant improvement in NYHA functional class.

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米尔顿瓣膜的临床经验：新型双叶机械假体在二尖瓣置换术中的短期效果。

目的：评价Miltonia双叶机械假体在二尖瓣置换术（MVR）中的性能。方法：本研究纳入了50例使用体外循环（CPB）和亚低温进行MVR的患者。术后给予标准的术后护理。术前、术后出院时和随访6个月时进行超声心动图检查，以评估血流动力学表现并检测不良事件。结果：平均年龄38.88±9.51岁，以女性患者为主。平均住院时间9.6±3.8天。术前88%的患者为纽约心脏协会（NYHA） III级，8%为IV级，4%为II级。术后改善至I级者92%，改善至II级者4% （p p p）。结论：密顿瓣膜血流动力学性能良好，NYHA功能分级明显改善。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Thoracic and Cardiovascular Surgery CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

1.20

自引率

14.30%

发文量

141

期刊介绍： The primary aim of the Indian Journal of Thoracic and Cardiovascular Surgery is education. The journal aims to dissipate current clinical practices and developments in the area of cardiovascular and thoracic surgery. This includes information on cardiovascular epidemiology, aetiopathogenesis, clinical manifestation etc. The journal accepts manuscripts from cardiovascular anaesthesia, cardiothoracic and vascular nursing and technology development and new/innovative products.The journal is the official publication of the Indian Association of Cardiovascular and Thoracic Surgeons which has a membership of over 1000 at present.DescriptionThe journal is the official organ of the Indian Association of Cardiovascular-Thoracic Surgeons. It was started in 1982 by Dr. Solomon Victor and ws being published twice a year up to 1996. From 2000 the editorial office moved to Delhi. From 2001 the journal was extended to quarterly and subsequently four issues annually have been printed out at time and regularly without fail. The journal receives manuscripts from members and non-members and cardiovascular surgeons. The manuscripts are peer reviewed by at least two or sometimes three or four reviewers who are on the panel. The manuscript process is now completely online. Funding the journal comes partially from the organization and from revenue generated by subscription and advertisement.