Timing performance evaluation of a dual-Axis rotational PET system according to NEMA NU 4-2008 standards: A simulation study.

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
P M C C Encarnação, P M M Correia, F M Ribeiro, J F C A Veloso
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引用次数: 0

Abstract

Introduction:Positron Emission Tomography (PET) imaging's diagnostic accuracy is dependent on the scanner design and image quality, which is affected by several factors including the coincidence timing window (CTW). NEMA NU 4-2008 procedures are commonly used to assess and compare PET systems performance, including dual rotation technologies like easyPET.3D, known for high-spatial resolution and reduced parallax contribution.Aim:This study aims to identify easyPET.3D's optimal performance based on NEMA standards. In addition, explores the impact of different CTWs on PET image quality by comparing simulated electronics capable of a 300 ps CTW with a 40 ns CTW.Results:When the data is filtered by a 40 ns CTW, a sub-millimetre resolution at the field-of-view (FoV) centre and a constant behaviour in the radial direction are achieved. The absolute sensitivity was 0.18% with a maximum value of 0.31%, for a 15 mm transverse FoV. The noise equivalent count rate peaked at 18 MBq with 249 cps. Recovery coefficients ranged from 17% to 90%, and spilled-over ratios were 0.32 (water) and 0.41 (air).Conclusions:A shorter 300 ps CTW primarily impacted PET dynamic range, allowing higher activity acquisitions, with no significant changes in resolution and sensitivity under NEMA test conditions. As for the image quality test, the 300 ps CTW images have less background, better SOR values, and similar RC values when comparing the 40 ns CTW.

基于NEMA NU 4-2008标准的双轴旋转PET系统定时性能评估:仿真研究。
正电子发射断层扫描(PET)成像的诊断准确性取决于扫描仪的设计和图像质量,而图像质量又受到包括重合定时窗(CTW)在内的几个因素的影响。NEMA NU 4-2008程序通常用于评估和比较PET系统的性能,包括双旋转技术,如easyPET。3D,以高空间分辨率和减少视差贡献而闻名。目的:本研究旨在识别easyPET。3D的最佳性能基于NEMA标准。此外,通过比较300 ps CTW和40 ns CTW的模拟电子设备,探讨了不同CTW对PET图像质量的影响。结果:当数据被40 ns CTW过滤时,在视场(FoV)中心获得了亚毫米分辨率,并且在径向上具有恒定的行为。对于15mm横向视场,绝对灵敏度为0.18%,最大值为0.31%。噪声等效计数率最高为18 MBq,为249 cps。回收系数范围为17% ~ 90%,溢出比为0.32(水)和0.41(空气)。结论:较短的300 ps CTW主要影响PET动态范围,允许更高的活度采集,在NEMA测试条件下分辨率和灵敏度没有显著变化。在图像质量测试方面,与40 ns CTW相比,300 ps CTW图像的背景更少,SOR值更好,RC值相似。
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来源期刊
Biomedical Physics & Engineering Express
Biomedical Physics & Engineering Express RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.80
自引率
0.00%
发文量
153
期刊介绍: BPEX is an inclusive, international, multidisciplinary journal devoted to publishing new research on any application of physics and/or engineering in medicine and/or biology. Characterized by a broad geographical coverage and a fast-track peer-review process, relevant topics include all aspects of biophysics, medical physics and biomedical engineering. Papers that are almost entirely clinical or biological in their focus are not suitable. The journal has an emphasis on publishing interdisciplinary work and bringing research fields together, encompassing experimental, theoretical and computational work.
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