THE EFFECT OF PARTNER DELIVERY OF HIV SELF-TEST KITS ON HIV TESTING AND LINKAGE TO CARE IN PUBLIC CLINICS IN KENYA.

IF 2.9 3区医学 Q3 IMMUNOLOGY

JAIDS Journal of Acquired Immune Deficiency Syndromes Pub Date : 2025-03-26 DOI:10.1097/QAI.0000000000003662

Catherine Kiptinness, Nelly Mugo, Kenneth K Mugwanya, Kenneth Ngure, Paul Mwangi, Dominic M Githuku Dip, Njeri Wairimu, Alfred Osoti, Marianne Mureithi, Renee Heffron

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引用次数: 0

Abstract

Background: Partners of people living with HIV (PLHIV) at high risk of HIV acquisition are a target population who may benefit from innovative HIV testing strategies. We explored the effectiveness of the secondary distribution of HIVST kits by PLHIV enrolled in HIV care to catalyze testing and linkage to care.

Methods: A prospective interventional study was conducted at four Kenyan HIV clinics deploying two testing strategies sequentially to reach sexual partners of PLHIV: 1) invitation by PLHIV for clinic-based testing and 2) distribution of HIVST kits by PLHIV. PLHIV were newly diagnosed with HIV or had been using antiretroviral therapy (ART) for <6 months or were not virally suppressed, with a sexual partner of unknown HIV status or whose sexual partner had tested >3 months ago. In-person interviewer-administered surveys were conducted with partners to determine whether they completed HIV testing and were linked to any follow-up care.

Results: A total of 345 PLHIV (167 invitation and 178 HIVST) and 274 (79.4%) of their sexual partners (135 invitation and 139 HIVST) were enrolled. Partners were more likely to get tested (98.6% vs. 77.8%, PPR=1.27, 95% CI [1.16- 1.39]) and to link to care (71.9% vs. 50.3%, PPR=1.43, 95% CI [1.17 - 1.74]) during the HIVST phase compared to the clinic phase. Among the subset of partners who tested HIV-positive, all were linked to care.

Conclusion: HIVST delivery by PLHIV increased the frequency of HIV testing and linkage to care among their partners. This strategy warrants further investigation to determine its potential for scale-up.

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合作伙伴提供艾滋病毒自检包对肯尼亚公共诊所艾滋病毒检测和护理联系的影响。

背景：艾滋病毒感染者（PLHIV）感染风险高的伴侣是可能从创新的艾滋病毒检测策略中受益的目标人群。我们探讨了HIV护理登记的PLHIV二次分发HIV试剂盒的有效性，以促进检测和与护理的联系。方法：在肯尼亚的四家HIV诊所进行了一项前瞻性干预研究，这些诊所依次采用两种检测策略：1)由PLHIV邀请进行临床检测；2)由PLHIV分发HIV试剂盒。新诊断为HIV或在3个月前接受抗逆转录病毒治疗（ART）。由访谈者亲自管理的调查与合作伙伴进行，以确定他们是否完成了艾滋病毒检测并与任何后续护理相关联。结果：共纳入PLHIV 345例（邀请167例，hiv感染者178例）及其性伴侣274例（79.4%）（邀请135例，hiv感染者139例）。与临床阶段相比，伴侣更有可能在hiv期接受检测（98.6%对77.8%，PPR=1.27, 95% CI[1.16- 1.39]），并与护理联系（71.9%对50.3%，PPR=1.43, 95% CI[1.17 - 1.74]）。在艾滋病毒检测呈阳性的部分伴侣中，所有人都得到了护理。结论：艾滋病毒携带者分娩后，其伴侣之间的艾滋病毒检测频率和护理联系增加。这一战略值得进一步调查，以确定其扩大规模的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

JAIDS Journal of Acquired Immune Deficiency Syndromes 医学-传染病学

CiteScore

5.80

自引率

5.60%

发文量

490

审稿时长

3-6 weeks

期刊介绍： JAIDS: Journal of Acquired Immune Deficiency Syndromes seeks to end the HIV epidemic by presenting important new science across all disciplines that advance our understanding of the biology, treatment and prevention of HIV infection worldwide. JAIDS: Journal of Acquired Immune Deficiency Syndromes is the trusted, interdisciplinary resource for HIV- and AIDS-related information with a strong focus on basic and translational science, clinical science, and epidemiology and prevention. Co-edited by the foremost leaders in clinical virology, molecular biology, and epidemiology, JAIDS publishes vital information on the advances in diagnosis and treatment of HIV infections, as well as the latest research in the development of therapeutics and vaccine approaches. This ground-breaking journal brings together rigorously peer-reviewed articles, reviews of current research, results of clinical trials, and epidemiologic reports from around the world.