A Mathematical Model for the Intracellular Accumulation of two Energy Reserve Carbohydrates in S. cerevisiae Cultures

Q3 Engineering

IFAC-PapersOnLine Pub Date : 2025-01-01 DOI:10.1016/j.ifacol.2025.03.070

Antoine Huet , Mihaela Sbarciog , Philippe Bogaerts

引用次数: 0

Abstract

This paper presents the development of a novel macroscopic model that predicts the dynamics of trehalose and glycogen in yeast Saccharomyces cerevisiae fed-batch cultures. The model includes storage and mobilization reactions for each reserve carbohydrate and conversion of glycogen to trehalose. The proposed model is a purely macroscopic model, which relates the two carbohydrates only to the variation of the extracellular components without including complex intracellular phenomena. Its predictions are in agreement with the experimental data. The model can be used to optimize the accumulation of the two reserve carbohydrates, to obtain yeast cells that can withstand stressful conditions.

查看原文本刊更多论文

麦角菌培养物中两种能量储备碳水化合物细胞内积累的数学模型

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

IFAC-PapersOnLine Engineering-Control and Systems Engineering

CiteScore

1.70

自引率

0.00%

发文量

1122

期刊介绍： All papers from IFAC meetings are published, in partnership with Elsevier, the IFAC Publisher, in theIFAC-PapersOnLine proceedings series hosted at the ScienceDirect web service. This series includes papers previously published in the IFAC website.The main features of the IFAC-PapersOnLine series are: -Online archive including papers from IFAC Symposia, Congresses, Conferences, and most Workshops. -All papers accepted at the meeting are published in PDF format - searchable and citable. -All papers published on the web site can be cited using the IFAC PapersOnLine ISSN and the individual paper DOI (Digital Object Identifier). The site is Open Access in nature - no charge is made to individuals for reading or downloading. Copyright of all papers belongs to IFAC and must be referenced if derivative journal papers are produced from the conference papers. All papers published in IFAC-PapersOnLine have undergone a peer review selection process according to the IFAC rules.