Application and Analysis of the Enhanced Recovery After Surgery Opioid Prescription Protocol in Arthroscopy and Arthroplasty Patients.

IF 2.6 2区 医学 Q1 ORTHOPEDICS
Wali U Pirzada, Simran Shamith, Thalia Le, Terence L Thomas, Sina Ramtin, Asif M Ilyas
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引用次数: 0

Abstract

Introduction: Surgery and postoperative opioid prescriptions are critical periods for potential drug dependence and diversion. Enhanced recovery after surgery (ERAS) pathways aim to improve patient outcomes by leveraging preoperative education, emphasizing nonopioid pain management, and using less invasive surgical techniques. The study hypothesis was that the use of ERAS pathways would decrease postoperative opioid prescribing after arthroscopy and arthroplasty surgeries.

Methods: A retrospective chart review was conducted on patients treated by 11 orthopaedic surgeons at 9 Iowa hospitals from November 2022 to March 2024. Patients were divided into arthroplasty (n = 67) and arthroscopy (n = 33) cohorts. Opioids prescribed before and after ERAS implementation were measured and converted to morphine milligram equivalents (MMEs). Statistical analyses included the Wilcoxon signed rank test, Mann-Whitney U test, and chi-squared test.

Results: The mean pre-ERAS prescription size was 389 MMEs (range: 140 to 900 MMEs) for the overall cohort postoperatively, with arthroplasty at 451 MMEs (range: 200 to 900 MMEs) and arthroscopy at 264 MMEs (range: 140 to 450 MMEs). After ERAS, the overall mean size dropped to 194 MMEs (range: 38 to 600 MMEs), with arthroplasty at 210 MMEs (range: 38 to 600 MMEs) and arthroscopy at 161 MMEs (range: 45 to 315 MMEs). Both cohorts saw significant reductions, with a mean 47% reduction in arthroplasty and a mean 33% reduction in arthroscopy (both P < 0.001). Statistical analysis found percent reduction of prescription size to be greater in the arthroplasty cohort than in the arthroscopy cohort (P < 0.001). Arthroscopy patients had a higher mean percentage of MMEs prescribed leftover (60%) compared with arthroplasty patients (27%; P< 0.001).

Conclusion: The study hypothesis was upheld as ERAS pathways resulted in a notable reduction in prescribing of opioids postoperatively after both arthroplasty and arthroscopic surgeries. ERAS pathways should continue to be tailored and studied to improve postoperative recovery while decreasing the reliance on opioids postoperatively for pain management.

关节镜手术和关节置换术患者术后阿片类药物处方强化恢复方案的应用与分析。
手术和术后阿片类药物处方是潜在药物依赖和转移的关键时期。增强术后恢复(ERAS)途径旨在通过术前教育、强调非阿片类疼痛管理和使用微创手术技术来改善患者预后。研究假设ERAS通路的使用将减少关节镜和关节置换术后阿片类药物的处方。方法:对2022年11月至2024年3月爱荷华州9家医院11名骨科医生治疗的患者进行回顾性图表分析。患者被分为关节成形术组(n = 67)和关节镜组(n = 33)。测量ERAS实施前后处方的阿片类药物并将其转换为吗啡毫克当量(MMEs)。统计分析包括Wilcoxon sign rank检验、Mann-Whitney U检验和卡方检验。结果:整个队列术后eras前处方平均为389 MMEs(范围:140至900 MMEs),关节置换术为451 MMEs(范围:200至900 MMEs),关节镜为264 MMEs(范围:140至450 MMEs)。ERAS后,整体平均大小降至194个MMEs(范围:38至600个MMEs),其中关节置换术为210个MMEs(范围:38至600个MMEs),关节镜检查为161个MMEs(范围:45至315个MMEs)。两个队列均有显著降低,关节置换术平均降低47%,关节镜平均降低33%(均P < 0.001)。统计分析发现,关节置换术组处方尺寸减少的百分比大于关节镜组(P < 0.001)。关节镜患者的MMEs处方剩余平均百分比(60%)高于关节置换术患者(27%;P < 0.001)。结论:研究假设得到支持,ERAS通路导致关节置换术和关节镜手术后阿片类药物处方显著减少。应继续定制和研究ERAS通路,以改善术后恢复,同时减少术后对阿片类药物的依赖。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.10
自引率
6.20%
发文量
529
审稿时长
4-8 weeks
期刊介绍: The Journal of the American Academy of Orthopaedic Surgeons was established in the fall of 1993 by the Academy in response to its membership’s demand for a clinical review journal. Two issues were published the first year, followed by six issues yearly from 1994 through 2004. In September 2005, JAAOS began publishing monthly issues. Each issue includes richly illustrated peer-reviewed articles focused on clinical diagnosis and management. Special features in each issue provide commentary on developments in pharmacotherapeutics, materials and techniques, and computer applications.
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