{"title":"A new preclinical sheep model of medial meniscus anterior root repair: Part 1-Quantitative morphology and relationships to adjacent structures.","authors":"Wei Liu, Marta Carretero-Hernández, Yin Zhang, Magali Cucchiarini, Matthias Brockmeyer, Henning Madry","doi":"10.1002/ksa.12656","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To analyse the quantitative morphology of the menisci, their roots and relations with a focus on the medial meniscus anterior root (MAR) as a basis for a preclinical model.</p><p><strong>Methods: </strong>Data was obtained from 24 tibial plateaus of skeletally mature, female Merino ewes. The MAR attachment (MARA) was scanned with micro-computed tomography and stained with hematoxylin and eosin. Data of relevant anatomical structures was subjected to principal component analysis (PCA) and Spearman correlations.</p><p><strong>Results: </strong>The osteo-ligamentous junction of the MARA represents a classical enthesis with a type-I insertion into the cortical bone. The medial tibial plateau was of a significantly smaller area than lateral. Its sagittal length was significantly longer than lateral. The widths of the MAR and lateral meniscus anterior root (LAR) were approximately half of both anterior horn widths. The MAR was significantly wider than the LAR. The medial meniscus body, posterior horn and medial posterior root were significantly thinner than lateral. PCA and cluster analysis revealed a striking, significant distinction between the structures of the medial and lateral tibial plateau. The sagittal length of the articular cartilage of both tibial plateaus correlated with the primary axis length of both menisci. The maximum width of the articular cartilage of both plateaus correlated with the area of both menisci. Significant correlations also existed between the length of the MAR and the total width of the tibia plateau and between the size of the MARA and the coronal distance to the medial tibial eminence (MTE), to the tibial tuberosity and the sagittal distance to the MTE.</p><p><strong>Conclusion: </strong>The ovine MAR may be appropriate for repair approaches because of its morphological similarities to the human situation. The substantial differences between the medial and lateral tibial plateau have to be respected.</p><p><strong>Level of evidence: </strong>Not applicable.</p>","PeriodicalId":17880,"journal":{"name":"Knee Surgery, Sports Traumatology, Arthroscopy","volume":" ","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Knee Surgery, Sports Traumatology, Arthroscopy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/ksa.12656","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: To analyse the quantitative morphology of the menisci, their roots and relations with a focus on the medial meniscus anterior root (MAR) as a basis for a preclinical model.
Methods: Data was obtained from 24 tibial plateaus of skeletally mature, female Merino ewes. The MAR attachment (MARA) was scanned with micro-computed tomography and stained with hematoxylin and eosin. Data of relevant anatomical structures was subjected to principal component analysis (PCA) and Spearman correlations.
Results: The osteo-ligamentous junction of the MARA represents a classical enthesis with a type-I insertion into the cortical bone. The medial tibial plateau was of a significantly smaller area than lateral. Its sagittal length was significantly longer than lateral. The widths of the MAR and lateral meniscus anterior root (LAR) were approximately half of both anterior horn widths. The MAR was significantly wider than the LAR. The medial meniscus body, posterior horn and medial posterior root were significantly thinner than lateral. PCA and cluster analysis revealed a striking, significant distinction between the structures of the medial and lateral tibial plateau. The sagittal length of the articular cartilage of both tibial plateaus correlated with the primary axis length of both menisci. The maximum width of the articular cartilage of both plateaus correlated with the area of both menisci. Significant correlations also existed between the length of the MAR and the total width of the tibia plateau and between the size of the MARA and the coronal distance to the medial tibial eminence (MTE), to the tibial tuberosity and the sagittal distance to the MTE.
Conclusion: The ovine MAR may be appropriate for repair approaches because of its morphological similarities to the human situation. The substantial differences between the medial and lateral tibial plateau have to be respected.
期刊介绍：
Few other areas of orthopedic surgery and traumatology have undergone such a dramatic evolution in the last 10 years as knee surgery, arthroscopy and sports traumatology. Ranked among the top 33% of journals in both Orthopedics and Sports Sciences, the goal of this European journal is to publish papers about innovative knee surgery, sports trauma surgery and arthroscopy. Each issue features a series of peer-reviewed articles that deal with diagnosis and management and with basic research. Each issue also contains at least one review article about an important clinical problem. Case presentations or short notes about technical innovations are also accepted for publication.
The articles cover all aspects of knee surgery and all types of sports trauma; in addition, epidemiology, diagnosis, treatment and prevention, and all types of arthroscopy (not only the knee but also the shoulder, elbow, wrist, hip, ankle, etc.) are addressed. Articles on new diagnostic techniques such as MRI and ultrasound and high-quality articles about the biomechanics of joints, muscles and tendons are included. Although this is largely a clinical journal, it is also open to basic research with clinical relevance.
Because the journal is supported by a distinguished European Editorial Board, assisted by an international Advisory Board, you can be assured that the journal maintains the highest standards.
Official Clinical Journal of the European Society of Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA).
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