Risk factors for in-hospital venous thromboembolism in patients with bladder cancer: A retrospective single-center study.

IF 3.4 2区医学 Q2 ONCOLOGY

BMC Cancer Pub Date : 2025-03-24 DOI:10.1186/s12885-025-13939-x

Huitang Yang, Tonghe Zhang, Zhaoyang Li, Yandong Cai, Zhan Jiang, Guoju Fan, Kaiqiang Wang, Bo Chen, Hongwei Zhang, Hailong Hu, Yankui Li

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引用次数: 0

Abstract

Objective: In this study, we retrospectively analyzed the incidence of and risk factors for in-hospital venous thromboembolism (VTE) in patients with bladder cancer and explored measures to reduce the incidence of and/or prevent in-hospital VTE and mortality.

Methods: The clinical data of 5744 patients with bladder cancer who were admitted to the Second Hospital of Tianjin Medical University during a 5-year period were summarized and then analyzed to determine the risk factors for in-hospital VTE in patients with bladder cancer with the aim of identifying preventive measures.

Results: Univariate analysis revealed significant differences between the VTE group and the non-VTE group in terms of age, sex, Caprini score, surgical treatment status, tumor stage, D-dimer level, PT, APTT, and Hb (P < 0.05). Multiple factor analysis further confirmed that the Caprini score, surgical treatment status, D-dimer level, PT, and APTT were independent risk factors for VTE.

Conclusion: Analyses revealed that a high Caprini score, surgical treatment, an elevated D-dimer level, a short PT, and a short APTT were independent risk factors for in-hospital VTE in patients with bladder cancer and that active preventive measures should be implemented to reduce the incidence of in-hospital VTE as well as mortality.

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来源期刊

BMC Cancer 医学-肿瘤学

CiteScore

6.00

自引率

2.60%

发文量

1204

审稿时长

6.8 months

期刊介绍： BMC Cancer is an open access, peer-reviewed journal that considers articles on all aspects of cancer research, including the pathophysiology, prevention, diagnosis and treatment of cancers. The journal welcomes submissions concerning molecular and cellular biology, genetics, epidemiology, and clinical trials.