An approach to subcritical fluid and natural deep eutectic solvent-ultrasound assisted extractions as green alternatives for Pecan nutshell phenolic compounds recovery

IF 3.5 2区农林科学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Food and Bioproducts Processing Pub Date : 2025-03-20 DOI:10.1016/j.fbp.2025.03.005

Miguel Esteban Cardona Jimenez , Andrea Carolina Rodríguez-Ruiz , Alexis Velez , Lina Marcela Agudelo-Laverde , Romina Mariana Bodoira , Patricio Román Santagapita

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引用次数: 0

Abstract

Green alternatives for Pecan nutshell phenolic compounds recovery were assessed in the present work. Subcritical fluid extraction and ultrasound-assisted extraction with natural deep eutectic solvent were optimized to maximize phenolic compounds extraction and antioxidant activities. Subcritical fluid was analyzed by varying temperature (180–220°C), flow rate (2.5–7.5 g/min) and solvent composition (0–100 % (v/v) ethanol/water mixtures). The optimal Subcritical fluid method involved operating at 220°C with 50 % (v/v) ethanol/water at a flow rate of 5 g/min, resulting in a remarkable 200 % increase on total phenolic compounds and a substantial 500 % increase on antioxidant activity measured by ferric reducing ability of plasma when compared to stirring, a conventional method used as control. Moreover, several ultrasound-assisted extractions with natural deep eutectic solvent were produced with choline chloride and lactic or malic acids; after selecting choline chloride-malic acid, the ratio and water % were optimized through response surface methodology. The optimal ultrasound-assisted extraction with natural deep eutectic solvent employed a 1:1 mol:mol ratio, with a water content of 35.82 % (v/v), yielding a 39 % and 25 % increase on total phenolic compounds and ferric reducing ability of plasma compared to stirring, respectively. Finally, a full evaluation of the most relevant characteristics regarding process, estimation of equipment and extraction costs and a comparison regarding simplicity, safety, selectivity, cost vs. benefit and applicability among the employed methods was included. This research contributes to the development of environmentally friendly technologies and its advantages/drawbacks applied to phenolic compounds recovery from Pecan nutshell with potential applications in food, cosmetics and pharmaceutical industries.

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来源期刊

Food and Bioproducts Processing 工程技术-工程：化工

CiteScore

9.70

自引率

4.30%

发文量

115

审稿时长

24 days

期刊介绍： Official Journal of the European Federation of Chemical Engineering: Part C FBP aims to be the principal international journal for publication of high quality, original papers in the branches of engineering and science dedicated to the safe processing of biological products. It is the only journal to exploit the synergy between biotechnology, bioprocessing and food engineering. Papers showing how research results can be used in engineering design, and accounts of experimental or theoretical research work bringing new perspectives to established principles, highlighting unsolved problems or indicating directions for future research, are particularly welcome. Contributions that deal with new developments in equipment or processes and that can be given quantitative expression are encouraged. The journal is especially interested in papers that extend the boundaries of food and bioproducts processing. The journal has a strong emphasis on the interface between engineering and food or bioproducts. Papers that are not likely to be published are those: • Primarily concerned with food formulation • That use experimental design techniques to obtain response surfaces but gain little insight from them • That are empirical and ignore established mechanistic models, e.g., empirical drying curves • That are primarily concerned about sensory evaluation and colour • Concern the extraction, encapsulation and/or antioxidant activity of a specific biological material without providing insight that could be applied to a similar but different material, • Containing only chemical analyses of biological materials.