Association of Perioperative Nursing Care with Incidence of Surgical Site Infections and Short-Term Outcomes in Primary Liver Cancer Patients: A Retrospective Comparison with Standard Care.

IF 2.8 3区 医学 Q1 Pharmacology, Toxicology and Pharmaceutics
Therapeutics and Clinical Risk Management Pub Date : 2025-03-17 eCollection Date: 2025-01-01 DOI:10.2147/TCRM.S512226
Bin Yang, Xiaoyun Guo, Kewen Qi, Shaolong Sun
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Abstract

Background: Surgical site infections (SSIs) are a significant complication following liver surgery (LS) for primary liver cancer (PLC), contributing to increased morbidity, prolonged hospital stays, and higher healthcare costs. This study aimed to evaluate the association of perioperative nursing care (PNC) with the incidence of SSIs and short-term outcomes, comparing patients receiving structured PNC to those receiving standard care.

Methods: A retrospective study was conducted at [specific location] between January 2016 and February 2019. A total of 360 PLC patients undergoing LS were included and divided into an observation group (PNC) and a control group (standard care). Outcome measures included SSI incidence, length of hospital stay, and independent predictors of SSIs. Logistic regression analysis was used to identify significant factors.

Results: Among the 360 included PLC patients, 180 received PNC while 180 did not. Patients in the PLC group had a significantly lower incidence of SSIs (28.3% vs 47.2%, P = 0.026) and shorter hospital stays (median: 8.2 vs 13.3 days, P = 0.049) compared to the control group. Multivariate logistic regression identified PNC as a significant protective factor against SSIs (OR = 2.01, 95% CI: 1.08-3.85, P = 0.031). Other significant predictors included education level (college or above: OR = 0.44, 95% CI: 0.24-0.79, P = 0.006) and comorbidities (more than two: OR = 2.21, 95% CI: 1.31-3.76, P = 0.003).

Conclusion: PNC emerged as an independent risk factor for SSIs in PLC patients undergoing LS. Thus, the provision of PNC is crucial for reducing the risk of SSIs and improving short-term outcomes in PLC patients undergoing LS.

原发性肝癌患者围手术期护理与手术部位感染发生率及短期预后的关系:与标准护理的回顾性比较
背景:手术部位感染(ssi)是原发性肝癌(PLC)肝手术(LS)后的重要并发症,导致发病率增加、住院时间延长和医疗费用增加。本研究旨在评估围手术期护理(PNC)与ssi发生率和短期预后的关系,将接受结构化PNC的患者与接受标准护理的患者进行比较。方法:2016年1月至2019年2月在[特定地点]进行回顾性研究。共纳入360例行LS的PLC患者,分为观察组(PNC)和对照组(标准治疗组)。结果测量包括SSI发生率、住院时间和SSI的独立预测因子。采用Logistic回归分析确定显著因素。结果:在360例PLC患者中,180例接受了PNC治疗,180例未接受PNC治疗。与对照组相比,PLC组患者ssi发生率显著降低(28.3% vs 47.2%, P = 0.026),住院时间缩短(中位数:8.2 vs 13.3天,P = 0.049)。多因素logistic回归发现PNC是预防ssi的重要保护因素(OR = 2.01, 95% CI: 1.08-3.85, P = 0.031)。其他重要的预测因素包括教育水平(大学及以上学历:or = 0.44, 95% CI: 0.24-0.79, P = 0.006)和合并症(超过两项:or = 2.21, 95% CI: 1.31-3.76, P = 0.003)。结论:PNC是PLC患者行LS后发生ssi的独立危险因素。因此,提供PNC对于降低ssi的风险和改善接受LS的PLC患者的短期预后至关重要。
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来源期刊
Therapeutics and Clinical Risk Management
Therapeutics and Clinical Risk Management HEALTH CARE SCIENCES & SERVICES-
CiteScore
5.30
自引率
3.60%
发文量
139
审稿时长
16 weeks
期刊介绍: Therapeutics and Clinical Risk Management is an international, peer-reviewed journal of clinical therapeutics and risk management, focusing on concise rapid reporting of clinical studies in all therapeutic areas, outcomes, safety, and programs for the effective, safe, and sustained use of medicines, therapeutic and surgical interventions in all clinical areas. The journal welcomes submissions covering original research, clinical and epidemiological studies, reviews, guidelines, expert opinion and commentary. The journal will consider case reports but only if they make a valuable and original contribution to the literature. As of 18th March 2019, Therapeutics and Clinical Risk Management will no longer consider meta-analyses for publication. The journal does not accept study protocols, animal-based or cell line-based studies.
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