Anna Kamdar, Jocelyn M Friday, Tran Q B Tran, Clea du Toit, Alan Stevenson, Jim D Lewsey, Colin Berry, Denise Brown, Claire E Hastie, Michael Fleming, Claudia Geue, Daniel F Mackay, Ruth Dundas, Christian Delles, Naveed Sattar, Sandosh Padmanabhan, Jill Pell, Frederick K Ho
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引用次数: 0
Abstract
Objective: Historical reductions in cardiovascular disease (CVD) due to lifestyle and treatment improvements are now threatened by factors such as increasing obesity and diabetes, but the relative importance of different risk factors varies by CVD condition. This study describes secular trends in CVD events by individual condition from 2012 to 2022.
Methods: In a cohort of 452 094 Greater Glasgow and Clyde residents aged ≥51 years, linked hospital admission and death data were used to ascertain total annual events for ischaemic heart disease (IHD), myocardial infarction (MI), heart failure (HF), atrial fibrillation (AF), stroke, abdominal aortic aneurysm (AAA) and peripheral artery disease (PAD). Poisson regressions with robust standard errors were used to examine the relative change in event rates over time, overall and by subgroup.
Results: Overall, the event rate ratios (RRs) for IHD, MI, AF and AAA all fell between 2012 and 2021 after adjustment for age, sex and deprivation. However, on subgroup analysis, the RRs increased between 2012 and 2022 among those aged 51-64 years for HF (RR 1.5), stroke (RR 1.4) and PAD (RR 1.8).
Conclusions: Overall declines in most types of CVD mask an increasing burden of events relating to HF, stroke and PAD among individuals aged 51-64 years.
期刊介绍:
Open Heart is an online-only, open access cardiology journal that aims to be “open” in many ways: open access (free access for all readers), open peer review (unblinded peer review) and open data (data sharing is encouraged). The goal is to ensure maximum transparency and maximum impact on research progress and patient care. The journal is dedicated to publishing high quality, peer reviewed medical research in all disciplines and therapeutic areas of cardiovascular medicine. Research is published across all study phases and designs, from study protocols to phase I trials to meta-analyses, including small or specialist studies. Opinionated discussions on controversial topics are welcomed. Open Heart aims to operate a fast submission and review process with continuous publication online, to ensure timely, up-to-date research is available worldwide. The journal adheres to a rigorous and transparent peer review process, and all articles go through a statistical assessment to ensure robustness of the analyses. Open Heart is an official journal of the British Cardiovascular Society.