K2O effect on structural, hardness, and bioactivity of sodium calcium silicate bioglasses

IF 4.3 3区材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

Materials Chemistry and Physics Pub Date : 2025-03-13 DOI:10.1016/j.matchemphys.2025.130719

Navneet Kaur Mattu , Priyankar Dey , K. Singh

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引用次数: 0

Abstract

Bioactive glasses and glass ceramics have been synthesized using various precursors with different processing parameters to enhance and optimize the developed material's bioactive properties. In the present study, the structural, mechanical, and bioactive properties of 43SiO₂–25CaO-(25-x)Na₂O-(x)K₂O–7P₂O₅ (x = 0, 5, 10, and 15 wt%) bioactive glasses, synthesized using a hybrid approach with agro-food waste-derived and conventional sources, were investigated to determine the impact of mixed alkali modification and K₂O substitution. Increased K₂O content enhanced the formation of the carbonated-hydroxyapatite (c-HAp) layer upon in-vitro testing. Interestingly, cell viability assays on human peripheral blood mononuclear cells (PBMC) confirmed non-toxicity at 10–200 μg/ml concentrations and up to 48 h at 100 μg/ml. This work shows that bioglass synthesized using hybrid chemical sources is unique, cost-effective, and non-toxic in a wide range of amounts with better and fast formation of c-HAp. The developed glasses exhibited comparable mechanical properties as reported for bioglasses synthesized using conventional sources.

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来源期刊

Materials Chemistry and Physics 工程技术-材料科学：综合

CiteScore

8.70

自引率

4.30%

发文量

1515

审稿时长

69 days

期刊介绍： Materials Chemistry and Physics is devoted to short communications, full-length research papers and feature articles on interrelationships among structure, properties, processing and performance of materials. The Editors welcome manuscripts on thin films, surface and interface science, materials degradation and reliability, metallurgy, semiconductors and optoelectronic materials, fine ceramics, magnetics, superconductors, specialty polymers, nano-materials and composite materials.