{"title":"Weighted sparsity regularization for solving the inverse EEG problem: A case study","authors":"Ole Løseth Elvetun, Niranjana Sudheer","doi":"10.1016/j.bspc.2025.107673","DOIUrl":null,"url":null,"abstract":"<div><div>We study the potential of detecting brain activity in terms of dipoles using weighted sparsity regularization. The work is based on theoretical results that we have proved in previous papers, but it requires modifications to fit into the classical EEG framework. In particular, to represent any dipole at a given position, we only need three basis dipoles with independent directions, but we will demonstrate that it might be beneficial to use more than three dipoles, i.e., a redundant basis/frame. This approach will, in fact, be more in line with the theoretical assumptions needed to guarantee the recovery of a single dipole. We demonstrate through several different experiments that the method does not suffer from the so-called depth bias, and we use standard measures to judge the ability of the method to recover one or two dipole sources. The results show that we do indeed find sparse solutions with relatively small dipole localization errors.</div></div>","PeriodicalId":55362,"journal":{"name":"Biomedical Signal Processing and Control","volume":"107 ","pages":"Article 107673"},"PeriodicalIF":4.9000,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical Signal Processing and Control","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1746809425001843","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
We study the potential of detecting brain activity in terms of dipoles using weighted sparsity regularization. The work is based on theoretical results that we have proved in previous papers, but it requires modifications to fit into the classical EEG framework. In particular, to represent any dipole at a given position, we only need three basis dipoles with independent directions, but we will demonstrate that it might be beneficial to use more than three dipoles, i.e., a redundant basis/frame. This approach will, in fact, be more in line with the theoretical assumptions needed to guarantee the recovery of a single dipole. We demonstrate through several different experiments that the method does not suffer from the so-called depth bias, and we use standard measures to judge the ability of the method to recover one or two dipole sources. The results show that we do indeed find sparse solutions with relatively small dipole localization errors.
期刊介绍:
Biomedical Signal Processing and Control aims to provide a cross-disciplinary international forum for the interchange of information on research in the measurement and analysis of signals and images in clinical medicine and the biological sciences. Emphasis is placed on contributions dealing with the practical, applications-led research on the use of methods and devices in clinical diagnosis, patient monitoring and management.
Biomedical Signal Processing and Control reflects the main areas in which these methods are being used and developed at the interface of both engineering and clinical science. The scope of the journal is defined to include relevant review papers, technical notes, short communications and letters. Tutorial papers and special issues will also be published.