Giada A. Beltramini , Edoardo F. Montrasio , Filippo Da Pozzo , Alessandro Cherchi , Domenico Sfondrini , Andrea Sacconi
{"title":"LogODDS as a prognostic factor in oral cavity squamous cell carcinoma","authors":"Giada A. Beltramini , Edoardo F. Montrasio , Filippo Da Pozzo , Alessandro Cherchi , Domenico Sfondrini , Andrea Sacconi","doi":"10.1016/j.suronc.2025.102213","DOIUrl":null,"url":null,"abstract":"<div><div>The objective of the study is to estimate the role of LogODDS as a prognostic factor in patients affected by oral cavity squamous cell carcinoma, in terms of overall survival (OS) and disease-free survival (DFS), looking for a cut-off value that allows to stratify them in high and low risk of recurrency, implementing the informations given by Lymph Node Ratio (LNR) and TNM 8th.</div><div>Seventyfour patients affected by oral cavity squamous cell carcinoma with metastatic lymph nodes who have undergone surgery at Maxillofacial Surgery Unit of the Fondazione IRCCS Cà Granda Ospedale Policlinico di Milano, in which a restaging according to TNM 8th was possible and LNR and LogODDS could have been calculated, were enrolled.</div><div>Multivariate analysis for OS was statistically relevant for both LogODDS and LNR, where N alone didn't reach the same result. No one of the previous parameters has a statistically relevant meaning in DFS prediction.</div><div>LogODDS as a prognostic factor has a statistically compelling meaning in order to predict overall survival in oral squamous cell carcinoma.</div></div>","PeriodicalId":51185,"journal":{"name":"Surgical Oncology-Oxford","volume":"60 ","pages":"Article 102213"},"PeriodicalIF":2.3000,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgical Oncology-Oxford","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0960740425000283","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The objective of the study is to estimate the role of LogODDS as a prognostic factor in patients affected by oral cavity squamous cell carcinoma, in terms of overall survival (OS) and disease-free survival (DFS), looking for a cut-off value that allows to stratify them in high and low risk of recurrency, implementing the informations given by Lymph Node Ratio (LNR) and TNM 8th.
Seventyfour patients affected by oral cavity squamous cell carcinoma with metastatic lymph nodes who have undergone surgery at Maxillofacial Surgery Unit of the Fondazione IRCCS Cà Granda Ospedale Policlinico di Milano, in which a restaging according to TNM 8th was possible and LNR and LogODDS could have been calculated, were enrolled.
Multivariate analysis for OS was statistically relevant for both LogODDS and LNR, where N alone didn't reach the same result. No one of the previous parameters has a statistically relevant meaning in DFS prediction.
LogODDS as a prognostic factor has a statistically compelling meaning in order to predict overall survival in oral squamous cell carcinoma.
期刊介绍:
Surgical Oncology is a peer reviewed journal publishing review articles that contribute to the advancement of knowledge in surgical oncology and related fields of interest. Articles represent a spectrum of current technology in oncology research as well as those concerning clinical trials, surgical technique, methods of investigation and patient evaluation. Surgical Oncology publishes comprehensive Reviews that examine individual topics in considerable detail, in addition to editorials and commentaries which focus on selected papers. The journal also publishes special issues which explore topics of interest to surgical oncologists in great detail - outlining recent advancements and providing readers with the most up to date information.