Sodium Oxybate: Practical Considerations and Patient Perspectives.

IF 7.4 2区医学 Q1 CLINICAL NEUROLOGY

CNS drugs Pub Date : 2025-03-01 Epub Date: 2025-03-20 DOI:10.1007/s40263-024-01144-6

Maggie Lavender, Cecile Martin, Diana Anderson

引用次数: 0

Abstract

Narcolepsy is a rare, chronic sleep disorder with significant impacts on the quality of life of people affected by the disorder. People with narcolepsy (PWN) are a diverse patient population with evolving symptoms, comorbidities, and perspectives. As PWN have varying needs, clinicians should consider a more personalized approach to therapy, including active participation of PWN in their care and shared decision-making between patient and clinician to achieve optimal outcomes. In this review, we discuss the various characteristics and challenges of PWN, present illustrative clinical case scenarios of PWN, provide clinicians with a proposed framework to best address therapy for PWN, and demystify concerns with sodium oxybate.

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羟丁酸钠：实际考虑因素和患者观点。

发作性睡病是一种罕见的慢性睡眠障碍，严重影响患者的生活质量。发作性睡病（PWN）患者是一个多样化的患者群体，具有不断发展的症状、合并症和观点。由于PWN有不同的需求，临床医生应该考虑更个性化的治疗方法，包括PWN积极参与他们的治疗，患者和临床医生共同决策，以实现最佳结果。在这篇综述中，我们讨论了PWN的各种特征和挑战，提出了PWN的说明性临床病例，为临床医生提供了一个建议的框架，以最佳地解决PWN的治疗问题，并消除了对氧化钠的担忧。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

CNS drugs 医学-精神病学

CiteScore

12.00

自引率

3.30%

发文量

审稿时长

6-12 weeks

期刊介绍： CNS Drugs promotes rational pharmacotherapy within the disciplines of clinical psychiatry and neurology. The Journal includes: - Overviews of contentious or emerging issues. - Comprehensive narrative reviews that provide an authoritative source of information on pharmacological approaches to managing neurological and psychiatric illnesses. - Systematic reviews that collate empirical evidence to answer a specific research question, using explicit, systematic methods as outlined by the PRISMA statement. - Adis Drug Reviews of the properties and place in therapy of both newer and established drugs in neurology and psychiatry. - Original research articles reporting the results of well-designed studies with a strong link to clinical practice, such as clinical pharmacodynamic and pharmacokinetic studies, clinical trials, meta-analyses, outcomes research, and pharmacoeconomic and pharmacoepidemiological studies. Additional digital features (including animated abstracts, video abstracts, slide decks, audio slides, instructional videos, infographics, podcasts and animations) can be published with articles; these are designed to increase the visibility, readership and educational value of the journal’s content. In addition, articles published in CNS Drugs may be accompanied by plain language summaries to assist readers who have some knowledge of, but not in-depth expertise in, the area to understand important medical advances.