Two siblings with tuberous xanthomas: case report.

Abstract

Tuberous xanthomas, a variety of the broad category of xanthomas, are a result of abnormalities in the lipoprotein metabolism, often familial in nature. These nodular swellings typically arise over the extensor aspect of the body, such as the elbows and the knees. A worrisome entity associated with them is the uncontrolled hyperlipidaemia, especially in young individuals. Here, we present two young brothers with such rare clinical signs and other manifestations of hyperlipidaemia, highlighting that thorough head-to-toe examination with the right set of investigations can aid in the diagnosis and management.