Confocal fluorescent study of the fish blood flukes: the serotonergic elements and ultrastructure of the nervous system of adult Sanguinicola plehnae (Digenea: Sanguinicolidae).

IF 1.5 4区医学 Q3 PARASITOLOGY

Folia Parasitologica Pub Date : 2025-03-11 DOI:10.14411/fp.2025.009

Larisa G Poddubnaya, Nadezhda B Terenina, Natalia D Kreshсhenko

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Abstract

The first data on the neurochemical and ultrastructural organisation of the nervous system of the fish blood fluke, suckerless adult Sanguinicola plehnae Warren et Bullard in Warren, Poddubnaya, Zhokhov, Reyda, Choudhury et Bullard, 2023 (Digenea: Aporocotylidae) from the circulatory system of pike, Esox lucius Linnaeus are presented. Based on 5-HT-IP staining, the simple, uniformly developed orthogonal pattern of S. plehnae nervous system is revealed. The ventral and dorsal nerve cords originate from the brain lobes, but the lateral nerve cords originate from anterior nerves at the level of the large serotonergic neurons. In addition, several pairs of such large 5-HT-IP neurons (22-23.5 µm in diameter) are revealed along the ventral nerve cords. Unusual spindle-shaped 5-HT-IP perikarya (7.8-19.8 µm in diameter) are observed along each ventral and lateral nerve cords. The neuroblasts and developing neurons are seen between neurites in S. plehnae along with neuron somata scattered around neuropil periphery, evidencing the renewal of neuron somata population in adult digeneans. The morphological variability of both the orthogonal pattern and neuron somata and types of neurovesicles in adult digeneans are discussed.

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鱼血吸虫的共聚焦荧光研究：血蛉成虫神经系统的5 -羟色胺能成分和超微结构。

本文首次报道了在Warren， Poddubnaya, Zhokhov, Reyda, Choudhury et Bullard， 2023年（Digenea: Aporocotylidae）从梭子鱼（Esox lucius Linnaeus）的循环系统中发现的无吸盘成年鱼血吸虫（Sanguinicola plehnae Warren et Bullard）神经系统的神经化学和超微结构组织。基于5-HT-IP染色，显示出简单、均匀发育的plehnae神经系统正交图。腹侧神经索和背侧神经索起源于脑叶，而侧侧神经索起源于大的血清素能神经元水平的前神经。此外，沿腹侧神经索可见几对这种大的5-HT-IP神经元（直径22-23.5µm）。沿每条腹侧和外侧神经索可见异常的纺锤状5-HT-IP核周（直径7.8-19.8µm）。成神经原细胞和发育中的神经元分布在神经突之间，神经元体分布在神经末梢周围，证明了成虫神经元体群的更新。讨论了成虫正交模式、神经元体和神经囊泡类型的形态学变异。

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来源期刊

Folia Parasitologica 医学-寄生虫学

CiteScore

2.70

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： FOLIA PARASITOLOGICA, issued in online versions, is an international journal that covers the whole field of general, systematic, ecological and experimental parasitology. It publishes original research papers, research notes and review articles. Contributions from all branches of animal parasitology, such as morphology, taxonomy, biology, biochemistry, physiology, immunology, molecular biology and evolution of parasites, and host-parasite relationships, are eligible. Novelty and importance in the international (not local or regional) context are required. New geographical records of parasites, records of new hosts, regional parasite and/or host surveys (if they constitute the principal substance of manuscript), local/regional prevalence surveys of diseases, local/regional studies on epidemiology of well known diseases and of parasite impact on human/animal health, case reports, routine clinical studies and testing of established diagnostic or treatment procedures, will not be considered. One species description will also not be considered unless they include more general information, such as new diagnostic characters, host-parasite associations, phylogenetic implications, etc. Manuscripts found suitable on submission will be reviewed by at least two reviewers.