A method for measuring spatial resolution based on clinical chest CT sequence images

IF 2 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Applied Clinical Medical Physics Pub Date : 2025-03-18 DOI:10.1002/acm2.70078

Ying Liu, Jingying Shen, Haowei Zhang, Haikuan Liu

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引用次数: 0

Abstract

Purpose

This study aimed to develop and validate a method for characterizing the spatial resolution of clinical chest computed tomography (CT) sequence images.

Methods

An algorithm for characterizing spatial resolution based on clinical chest CT sequence images was developed in Matlab (2021b). The algorithm was validated using CT sequence images from a custom-made chest automatic tube current modulation (ATCM) phantom and clinically reconstructed chest CT sequence images. A region of interest (ROI) was automatically established at the edges of CT image subject to calculate the edge spread function (ESF). The ESF curves from consecutive CT images within the same sequence were fitted into a curve, and the line spread function (LSF) was derived through differentiation. A Fourier transformation of the LSF curve was conducted to obtain the modulation transfer function (MTF). The method's effectiveness was verified by comparing the 50% MTF and 10% MTF values with those calculated using IndoQCT (22a) software. The method was also applied to clinical CT images to calculate MTF values for various reconstructions, confirming its sensitivity by determining spatial resolution of clinically reconstructed images.

Results

Validation experiments based on the phantom CT sequence images demonstrated that the MTF values calculated using the proposed method had an average difference of within ± 5% compared to the results obtained with IndoQCT. Validation experiments with clinical CT sequence images indicated that the method effectively reflects differences and variations in spatial resolution of images under different reconstruction kernels, with the MTF values for B10f-B50f and D10f-D50f exhibiting a consistent increase.

Conclusion

A method for measuring spatial resolution using clinical chest CT sequence images was developed. This method provides a direct means of spatial resolution characterization for clinical CT datasets and a more accurate representation of CT imaging quality, effectively reflects variations across different reconstruction convolution kernels, demonstrating its sensitivity.

Abstract Image

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一种基于临床胸部CT序列图像的空间分辨率测量方法。

目的：本研究旨在开发和验证一种表征临床胸部计算机断层扫描（CT）序列图像空间分辨率的方法。方法：在Matlab （2021b）中开发一种基于临床胸部CT序列图像的空间分辨率表征算法。通过定制胸部自动管电流调制（ATCM）模型的CT序列图像和临床重建的胸部CT序列图像对该算法进行了验证。在CT图像对象的边缘自动建立感兴趣区域（ROI），计算边缘扩展函数（ESF）。将同一序列内的连续CT图像的ESF曲线拟合成一条曲线，通过微分得到直线扩散函数（line spread function， LSF）。对LSF曲线进行傅里叶变换，得到调制传递函数（MTF）。通过将50% MTF和10% MTF值与IndoQCT （22a）软件计算的MTF值进行比较，验证了该方法的有效性。将该方法应用于临床CT图像，计算各种重建的MTF值，通过确定临床重建图像的空间分辨率来验证其灵敏度。结果：基于幻影CT序列图像的验证实验表明，使用本文方法计算的MTF值与使用IndoQCT计算的结果相比，平均误差在±5%以内。临床CT序列图像验证实验表明，该方法有效反映了不同重构核下图像空间分辨率的差异和变化，B10f-B50f和D10f-D50f的MTF值呈现一致的增大趋势。结论：建立了一种利用临床胸部CT序列图像测量空间分辨率的方法。该方法为临床CT数据集提供了一种直接的空间分辨率表征手段，更准确地表征了CT成像质量，有效反映了不同重建卷积核之间的变化，显示了其敏感性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Applied Clinical Medical Physics 医学-核医学

CiteScore

3.60

自引率

19.00%

发文量

331

审稿时长

3 months

期刊介绍： Journal of Applied Clinical Medical Physics is an international Open Access publication dedicated to clinical medical physics. JACMP welcomes original contributions dealing with all aspects of medical physics from scientists working in the clinical medical physics around the world. JACMP accepts only online submission. JACMP will publish: -Original Contributions: Peer-reviewed, investigations that represent new and significant contributions to the field. Recommended word count: up to 7500. -Review Articles: Reviews of major areas or sub-areas in the field of clinical medical physics. These articles may be of any length and are peer reviewed. -Technical Notes: These should be no longer than 3000 words, including key references. -Letters to the Editor: Comments on papers published in JACMP or on any other matters of interest to clinical medical physics. These should not be more than 1250 (including the literature) and their publication is only based on the decision of the editor, who occasionally asks experts on the merit of the contents. -Book Reviews: The editorial office solicits Book Reviews. -Announcements of Forthcoming Meetings: The Editor may provide notice of forthcoming meetings, course offerings, and other events relevant to clinical medical physics. -Parallel Opposed Editorial: We welcome topics relevant to clinical practice and medical physics profession. The contents can be controversial debate or opposed aspects of an issue. One author argues for the position and the other against. Each side of the debate contains an opening statement up to 800 words, followed by a rebuttal up to 500 words. Readers interested in participating in this series should contact the moderator with a proposed title and a short description of the topic