Accelerating Animal Replacement: How Universities Can Lead - Results of a One-Day Expert Workshop in Zurich, Switzerland.

IF 2.4 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Atla-Alternatives To Laboratory Animals Pub Date : 2025-03-01 Epub Date: 2025-03-16 DOI:10.1177/02611929251317434
Maneesha Deckha, Margot Michel, David Azilagbetor, Charlotte Blattner, Rosa Maria Cajiga Morales, Gail Davies, Bernice Elger, Sara Faizee, Marie Fox, Vanessa Gerritsen, Adrian Heuss, Laura Kämpfen, Edwin Louis-Maerten, Nicole Lüthi, Aoife Milford, Nico Dario Müller, Kirsten Persson, Merel Ritskes-Hoitinga, Barbara Rothen-Rutishauser, Andreas Rüttimann, Katerina Stoykova, Saskia Stucki, Miriam A Zemanova
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引用次数: 0

Abstract

This report is a result of an interdisciplinary workshop held at the Collegium Helveticum in Zurich, Switzerland in February 2024, in which ideas for accelerating NAMs (New Approach Methodologies) in Swiss universities were shared and discussed. Due to regional differences in university organisation and funding structures, not all recommendations will be transferable to all regions worldwide. All participants were qualified to contribute to the discussion, due to their knowledge and experience of the Three Rs, in particular with regard to their implementation. The workshop participants believed that universities, which play a pioneering role in so many other areas, should also exploit their innovative potential in the field of animal-free research. The workshop uncovered four areas that would need to be addressed in order to achieve a significant change in university science culture and do more justice to the Three Rs, namely: language - innovative framing (pro-replacement framing in official university statements); knowledge transfer - communicating innovative findings in teaching (redirecting curriculum); change of values within science faculties; and structured implementation and well-coordinated planning of the transformation (establishment of a 'transition unit'). Specific strategies for implementing these four areas are outlined. In addition, we discuss why the replacement of animal testing should be an essential goal for universities, why this goal has not yet been achieved, and why concerted efforts toward change are required.

加速动物替代:大学如何发挥领导作用——瑞士苏黎世为期一天的专家研讨会的结果。
这份报告是2024年2月在瑞士苏黎世赫尔维提姆学院举行的跨学科研讨会的结果,在研讨会上,瑞士大学加速NAMs(新方法方法)的想法得到了分享和讨论。由于大学组织和资助结构的地区差异,并非所有建议都适用于全球所有地区。所有与会者都有资格为讨论作出贡献,因为他们对“三个r”的知识和经验,特别是在执行方面。与会者认为,在许多其他领域发挥先锋作用的大学也应在无动物研究领域发挥创新潜力。研讨会揭示了四个需要解决的领域,以实现大学科学文化的重大变化,并更加公正地对待三个r,即:语言-创新框架(在官方大学声明中支持替代框架);知识转移-在教学中交流创新发现(重新调整课程);科学院系内部价值观的变迁以及转型的结构化实施和良好协调的规划(建立“转型单位”)。概述了实施这四个领域的具体战略。此外,我们还讨论了为什么替代动物实验应该是大学的一个基本目标,为什么这一目标尚未实现,以及为什么需要共同努力进行改变。
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来源期刊
CiteScore
3.80
自引率
3.70%
发文量
60
审稿时长
>18 weeks
期刊介绍: Alternatives to Laboratory Animals (ATLA) is a peer-reviewed journal, intended to cover all aspects of the development, validation, implementation and use of alternatives to laboratory animals in biomedical research and toxicity testing. In addition to the replacement of animals, it also covers work that aims to reduce the number of animals used and refine the in vivo experiments that are still carried out.
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