Electroacupuncture relieves type 2 diabetes by regulating gut microbiome.

IF 4.2 3区医学 Q1 ENDOCRINOLOGY & METABOLISM

World Journal of Diabetes Pub Date : 2025-03-15 DOI:10.4239/wjd.v16.i3.103032

Ya-Jing Yang, Xu-Chang Zhou, Hao-Ran Tian, Feng-Xia Liang

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引用次数: 0

Abstract

Cumulative studies have shown that the composition of the gut microbiome is strongly associated with the development of type 2 diabetes mellitus (T2DM). Electroacupuncture (EA) therapy has been reported to alleviate various diseases, including T2DM, by targeting specific acupuncture points and regulating metabolic homeostasis. A recent review published in the World Journal of Diabetes detailed the role of the gut microbiome in T2DM, discussing the role of therapeutic strategies developed to alleviate T2DM and its complications based on gut microbiome in ameliorating T2DM, as well as the effects of multiple diabetes medications on gut microbiome. However, the review did not elucidate the therapeutic role of EA therapy, a common non-pharmacological intervention for T2DM. This letter complemented the effect of EA therapy on glucose metabolism by adjusting the gut microbiome composition, which reveals the underlying mechanism of glucose lowering by EA therapy and provides a scientific basis for the application of EA therapy in clinical treatment.

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电针通过调节肠道微生物群缓解2型糖尿病。

累积研究表明，肠道微生物组的组成与2型糖尿病（T2DM）的发展密切相关。据报道，电针（EA）疗法通过靶向特定穴位和调节代谢稳态来缓解多种疾病，包括T2DM。最近发表在《世界糖尿病杂志》上的一篇综述详细介绍了肠道微生物组在T2DM中的作用，讨论了基于肠道微生物组的T2DM及其并发症的治疗策略在改善T2DM中的作用，以及多种糖尿病药物对肠道微生物组的影响。然而，该综述并没有阐明EA治疗的治疗作用，这是一种常见的非药物干预T2DM的方法。本研究补充了EA治疗通过调节肠道菌群组成对糖代谢的影响，揭示了EA治疗降糖的潜在机制，为EA治疗在临床治疗中的应用提供了科学依据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World Journal of Diabetes ENDOCRINOLOGY & METABOLISM-

自引率

2.40%

发文量

909

期刊介绍： The WJD is a high-quality, peer reviewed, open-access journal. The primary task of WJD is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of diabetes. In order to promote productive academic communication, the peer review process for the WJD is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJD are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in diabetes. Scope: Diabetes Complications, Experimental Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes, Gestational, Diabetic Angiopathies, Diabetic Cardiomyopathies, Diabetic Coma, Diabetic Ketoacidosis, Diabetic Nephropathies, Diabetic Neuropathies, Donohue Syndrome, Fetal Macrosomia, and Prediabetic State.