The intraoperative SEEG and 18FDG-PET tailored temporal lobe resection (iSP-TR) for the tissue-spearing surgical treatment of drug-resistant mesial temporal lobe epilepsy: how we do it

IF 1.9 3区医学 Q3 CLINICAL NEUROLOGY

Acta Neurochirurgica Pub Date : 2025-03-19 DOI:10.1007/s00701-025-06491-x

Francesca Battista, Riccardo Carrai, Antonello Grippo, Alessandro Della Puppa

引用次数: 0

Abstract

Background

For drug-resistant mesial temporal lobe epilepsy (MTLE), surgery is recommended. There is no evidence of a seizure outcome advantage of temporal lobectomy over other strategies despite the high risks of this surgical procedure.

Methods

We describe a Temporal Resection guided by intraoperative stereo-electroencephalography (iSEEG) and the ¹⁸FluoroDeoxyGlucose PET (¹⁸FDG PET) (iSP-TR) to treat lesional MTLE. We avoided functional cortical areas using navigated Transcranial Magnetic Stimulation (nTMS).

Conclusion

iSP-TR allows for a spare brain parenchyma compared to temporal lobectomy without compromising seizure outcomes.

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术中SEEG和18FDG-PET定制颞叶切除术（iSP-TR）用于组织穿刺手术治疗耐药内侧颞叶癫痫：我们是如何做到的

背景：对于耐药内侧颞叶癫痫（MTLE），推荐手术治疗。尽管颞叶切除术的风险很高，但没有证据表明颞叶切除术在癫痫发作结果上优于其他策略。方法采用术中立体脑电图（iSEEG）和18氟脱氧葡萄糖PET (18FDG PET) （iSP-TR）引导下颞叶切除治疗病变性MTLE。我们使用导航经颅磁刺激（nTMS）避开皮质功能区。结论：与颞叶切除术相比，isp - tr可以保留备用脑实质，而不会影响癫痫发作的结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Neurochirurgica 医学-临床神经学

CiteScore

4.40

自引率

4.20%

发文量

342

审稿时长

1 months

期刊介绍： The journal "Acta Neurochirurgica" publishes only original papers useful both to research and clinical work. Papers should deal with clinical neurosurgery - diagnosis and diagnostic techniques, operative surgery and results, postoperative treatment - or with research work in neuroscience if the underlying questions or the results are of neurosurgical interest. Reports on congresses are given in brief accounts. As official organ of the European Association of Neurosurgical Societies the journal publishes all announcements of the E.A.N.S. and reports on the activities of its member societies. Only contributions written in English will be accepted.