{"title":"[HLA antigens in patients with laryngeal cancer].","authors":"B Beleites, S Wegener, R Nowak, G Wilden","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The HLA-ABC- and -DR-antigens of patients with carcinoma of the larynx were determined. The frequencies were compared with those of a normal population. No significant deviations in the antigen frequencies were observed in the distribution of HLA antigens. Therefore, participation of HLA-ABC and -DR gene products in pathogenesis of carcinoma of the larynx as an expression of a genetical component cannot be postulated till now.</p>","PeriodicalId":76098,"journal":{"name":"Laryngologie, Rhinologie, Otologie","volume":"67 10","pages":"543-4"},"PeriodicalIF":0.0000,"publicationDate":"1988-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Laryngologie, Rhinologie, Otologie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The HLA-ABC- and -DR-antigens of patients with carcinoma of the larynx were determined. The frequencies were compared with those of a normal population. No significant deviations in the antigen frequencies were observed in the distribution of HLA antigens. Therefore, participation of HLA-ABC and -DR gene products in pathogenesis of carcinoma of the larynx as an expression of a genetical component cannot be postulated till now.