Comparison of Intrauterine and Postnatal Brain Magnetic Resonance Imaging: Systematic Review

IF 3.2 3区医学 Q2 CLINICAL NEUROLOGY

Pediatric neurology Pub Date : 2025-02-25 DOI:10.1016/j.pediatrneurol.2025.02.009

Anastasija Arechvo MD, PhD , Kypros H. Nicolaides MD , Elspeth H. Whitby MBChB, PhD , Anthony R. Hart MBChB, MRCPCH, PhD

{"title":"Comparison of Intrauterine and Postnatal Brain Magnetic Resonance Imaging: Systematic Review","authors":"Anastasija Arechvo MD, PhD , Kypros H. Nicolaides MD , Elspeth H. Whitby MBChB, PhD , Anthony R. Hart MBChB, MRCPCH, PhD","doi":"10.1016/j.pediatrneurol.2025.02.009","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Fetal magnetic resonance imaging (MRI) identifies brain abnormalities better than transabdominal ultrasound. Most studies compare fetal MRI with postnatal cranial ultrasound or postmortem, so it is unclear how useful postnatal MRI is after fetal MRI. This work aimed to review the literature on postnatal MRI compared with fetal MRI to determine whether it provided useful clinical information.</div></div><div><h3>Methods</h3><div>A literature search to April 2024 was performed to identify publications on fetal brain abnormalities examined using both fetal MRI and postnatal MRI. A systematic review was performed. The quality of research was evaluated using Joanna Briggs Institute checklists.</div></div><div><h3>Results</h3><div>We identified 24 studies of 401 participants. All identified papers were retrospective or prospective case series at high risk of bias. Fourteen (58.3%) of the studies were high or moderate quality and 10 (41.7%) were low. Postnatal MRI confirmed the findings of fetal MRI in 296 (73.8%), refuted the diagnosis on fetal MRI in 24 (6.2%), and found additional abnormalities in 81 (20.2%). The suspected abnormalities on fetal MRI not confirmed on postnatal MRI were 12 isolated inferior cerebellar vermis hypoplasia, eight cerebellar vermis cysts, one mild ventriculomegaly, and one each of focal white matter abnormality, mega cisterna magna, and an unstated abnormality. Two papers including 17 participants reported that postnatal MRI changed the management or prognosis in nine (52.9%) participants.</div></div><div><h3>Conclusions</h3><div>The evidence on the value of postnatal MRI following a diagnosis of fetal brain abnormality is limited in size and quality, and further prospective research evidence is required.</div></div>","PeriodicalId":19956,"journal":{"name":"Pediatric neurology","volume":"166 ","pages":"Pages 47-54"},"PeriodicalIF":3.2000,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric neurology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0887899425000505","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Fetal magnetic resonance imaging (MRI) identifies brain abnormalities better than transabdominal ultrasound. Most studies compare fetal MRI with postnatal cranial ultrasound or postmortem, so it is unclear how useful postnatal MRI is after fetal MRI. This work aimed to review the literature on postnatal MRI compared with fetal MRI to determine whether it provided useful clinical information.

Methods

A literature search to April 2024 was performed to identify publications on fetal brain abnormalities examined using both fetal MRI and postnatal MRI. A systematic review was performed. The quality of research was evaluated using Joanna Briggs Institute checklists.

Results

We identified 24 studies of 401 participants. All identified papers were retrospective or prospective case series at high risk of bias. Fourteen (58.3%) of the studies were high or moderate quality and 10 (41.7%) were low. Postnatal MRI confirmed the findings of fetal MRI in 296 (73.8%), refuted the diagnosis on fetal MRI in 24 (6.2%), and found additional abnormalities in 81 (20.2%). The suspected abnormalities on fetal MRI not confirmed on postnatal MRI were 12 isolated inferior cerebellar vermis hypoplasia, eight cerebellar vermis cysts, one mild ventriculomegaly, and one each of focal white matter abnormality, mega cisterna magna, and an unstated abnormality. Two papers including 17 participants reported that postnatal MRI changed the management or prognosis in nine (52.9%) participants.

Conclusions

The evidence on the value of postnatal MRI following a diagnosis of fetal brain abnormality is limited in size and quality, and further prospective research evidence is required.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Pediatric neurology 医学-临床神经学

CiteScore

4.80

自引率

2.60%

发文量

176

审稿时长

78 days

期刊介绍： Pediatric Neurology publishes timely peer-reviewed clinical and research articles covering all aspects of the developing nervous system. Pediatric Neurology features up-to-the-minute publication of the latest advances in the diagnosis, management, and treatment of pediatric neurologic disorders. The journal''s editor, E. Steve Roach, in conjunction with the team of Associate Editors, heads an internationally recognized editorial board, ensuring the most authoritative and extensive coverage of the field. Among the topics covered are: epilepsy, mitochondrial diseases, congenital malformations, chromosomopathies, peripheral neuropathies, perinatal and childhood stroke, cerebral palsy, as well as other diseases affecting the developing nervous system.